Algorithm for Calcium Deficiency Correction in Young Children with Food Allergy Manifestations
Journal Title: Здоров`я дитини - Year 2014, Vol 6, Issue 57
Abstract
Objective — to develop algorithm for calcium deficiency correction in young children with food allergy (FA) manifestations. Materials and Methods. We have examined 150 children aged 1 to 3 years age with FA and sensitization to cow’s milk protein and in two study groups: 1) I group — children with FA manifestations and the laboratory signs of calcium deficiency (n = 56); 2) II group — children with FA manifestations without the laboratory signs of calcium deficiency (n = 94). The level of total calcium, inorganic phosphorus and vitamin 25(OH)D3 in blood serum were investigated. Results. As a result of inspection 150 children with FA, we have found decline of serum calcium concentration in 56 children (37.3 %) (fluctuations of parameters from 2.08 to 2.24 mmol/l). The same situation was marked in relation to the level of serum inorganic phosphorus in children of I group (fluctuations of parameters from 1.42 to 1.54 mmol/l). When analyzing the content of vitamin D3 in blood serum, it was discovered, that in children from the study groups this index was within the limits of age-dependent norm (fluctuations of indexes from 24.21 to 26.81 ng/ml). There has been developed an algorithm of differentiated therapeutic and prophylactic measures, including localization, fixation and elimination of causally significant allergens (hypoallergic diet, sorbents), anti-inflammatory therapy (antihistamines, inhibitor of mast cell degranulation, local therapy), correcting therapy for disorders of osteogenesis processes. After the conducted correction, normalization of indexes of total calcium and inorganic phosphorus was marked in the blood serum of children from I study group has been noted. Conclusion. Developed algorithm for differentiated therapeutic and prophylactic measures enables to reduce of activity of allergic inflammatory process and to normalize indexes, characterizing the processes of osteogenesis in young children with food allergy.
Authors and Affiliations
O. V. Kryazhev, L. S. Ovcharenko, A. O. Vertegel, I. V. Samokhin, T. G. Andriyenko, N. V. Zhikhareva
Keywords
Related Articles
- EP ID EP317114
- DOI -
- Views 91
- Downloads 0
Features of Case Follow-up of Extremely Preterm Infants
Objective. The study was conducted to analyze and improve the quality of case follow-up of children with birth weight < 1000 g and gestational age ≤ 28 weeks. Materials and Methods. The study group comprised 42 children,...
Therapeutic correction of liver and biliary tract pathology among adolescents with obesity
Background. The purpose of the study is to evaluate the efficacy of hepatoprotectors in comprehensive treatment of adolescents with obesity, non-alcoholic fatty liver disease and dysfunctional disorders of the biliary tr...
Results of the Monitoring for BCG Vaccination Complications
BCG vaccination remains relevant because of the tense epidemiological situation on tuberculosis in Ukraine. BCG vaccines are safe, but when they are used, there is a risk of complications. In the Donetsk region, from 200...
Current and future etiologic therapy of bacterial pneumonia. 1. Antibiotic therapy for community-acquired pneumonia
The progressive increase in the prevalence of respiratory infections caused by multiresistant pathogenic agents is a serious problem requiring strict indications and development of algorithms for prescribing antibacteria...
Pathogenetic Mechanisms of Diarrhea in Children and Methods for Its Treatment
The paper presents the current views on the pathogenesis of acute intestinal infections in children and principles of therapy of diarrhea syndrome. Particular attention is paid to antisecretory therapy and the role of ra...