Alpha 2 agonist dexmedetomidine as an adjuvant to bupivacaine in supraclavicular brachial plexus block
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 5
Abstract
Background: Regional anesthesia is a recommended technique for upper limb surgeries with better postoperative profile. Alpha-2 agonists are added to local anesthetic agents to extend the duration of nerve blocks. We evaluated the effect of combining dexmedetomidine with bupivacaine with respect to duration of motor and sensory block and duration of analgesia. Materials and Methods: Sixty patients posted for upper limb surgeries were enrolled for a prospective, randomized, study. Patients were divided into two groups, the control group B and the study group BD. In group B (n = 30), 30 ml of 0.325% bupivacaine + normal saline; and in group BD (n = 30), 30 ml of 0.325% bupivacaine +1μg/kg dexmedetomidine given ultrasound guided supraclavicular brachial plexus block. Results: The onset times for sensory and motor blocks were significantly shorter in BD than B group (p < 0.05), while the duration of sensory and motor blocks was significantly longer in BD group. The duration of analgesia was significantly longer in BD group than B group (p < 0.0001). SBP and DBP levels in BD group were significantly lower than in B group 20 min after block (p < 0.001). Bradycardia was observed in two patients in the group BD. Conclusion: Dexmedetomidine added as an adjuvant to bupivacaine for supraclavicular brachial plexus block significantly shortens the onset time and prolongs the duration of sensory and motor blocks and duration of analgesia. Patients in group BD were adequately sedated with no adverse effects except bradycardia in two patients.
Authors and Affiliations
Vaishali Waindeskar, Abhilekh Jain, Jitendra Kumar, Anupam Pandey, Sheetal Songir
Keywords
Related Articles
- EP ID EP230172
- DOI 10.17511
- Views 140
- Downloads 0
Commissioning of two different algorithms for stereotactic Radiosurgery M6 FI+ CyberKnife system
Introduction: Cyber Knife M6 FI+ a very precise robotic stereotactic radiosurgery system which is capable of delivering very high radiation dose to the tumour while minimizing radiation exposure to normal organs and tiss...
Distribution of serum creatinine, calcium and protein levels in multiple myeloma patients - a hospital based study at Gauhati Medical College and Hospital, Guwahati, Assam
Introduction: Multiple Myeloma (MM) is a clonal plasma cell neoplasm characterized by the proliferation of plasma cells, monoclonal protein, Osteolytic bone lesions, renal disease and immunodeficiency. It accounts for 15...
Hydatid cyst-our institutional experience in hill area of Uttarakhand
Introduction: Hydatidosis caused by Echinococcus granulosus is a neglected zoonotic disease, widely prevalent among the rural population of India. Hepatic involvement is the commonest, with other varied presentations as...
Case report of a rare case of Non-hodgkin Lymphoma presenting as sternal mass
Primary or metastatic tumors of the chest wall constitute 5% of all thoracic tumors and lymphoma comprises about 2% of all chest wall tumors. We report a case of a 23year old male presenting with anterior chest wall mass...
Study of sternalis muscle in north Indian population- a cadaveric study
Background: Sternalis is anatomic variant of anterior thoracic region generally encountered on routine dissection, imaging procedures or surgeries. Although here is sufficient text available regarding presence and extent...