Altered Blood Glucose Levels in Polycystic Ovary Syndrome
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 5
Abstract
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder affecting 5-7% women of reproductive age. The etiology of PCOS is multifactorial. It is associated with menstrual dysfunction and subfertility. Hyperinsulinemia and insulin resistance are commonly associated with PCOS. Insulin resistance is now recognized as a major risk factor for development of hyperglycemia and type 2 diabetes mellitus. The Aims of present study is to know the blood glucose levels in women of younger age group with PCOS. A case control study was conducted in 50 non diabetic PCOS patients (15 to 25 years age) and 50 non diabetic normal menstruating women, matched for age and anthropometric data. 2 ml of fasting blood sample was collected for fasting blood sugar (FBS). 75 gram of glucose was given with 300ml of water to drink. After 2 hours, blood sample was collected for post prandial blood sugar (PPBS). Statistical analysis was done by using student‘t’ test. FBS and PPBS after 2 hour OGTT were significantly raised in PCOS patients compared to normal menstruating women. Periodic screening of PCOS patients should be carried out as they are more prone to develop glucose intolerance and diabetes mellitus and failing to do so the patient may end up in cardiovascular and other complication. Keywords: Polycystic ovary syndrome (PCOS), diabetes mellitus, blood glucose, Hyperinsulinemia.
Authors and Affiliations
Dr. Veena H. C, Dr. Reshmarani, Dr. Shilpa. N
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