Alternative Mathematical Form for Determining the Effectiveness of High-LET Radiations at Lower Doses Region
Journal Title: International Journal of Radiology and Imaging Technology - Year 2016, Vol 2, Issue 1
Abstract
The Effectiveness of lower doses of high-LET radiations is not accurately determined by using energy-based physical parameters such as absorbed dose and radio-sensitivity parameters. Therefore, an attempt has been carried out in this research to propose alternative parameter that capable to quantify the effectiveness of these high LET radiations at lower doses regions. The linear energy transfer and mean free path for linear primary ionization are employed as distinct parameters to achieve this objective. A new mathematical form of the effectiveness of high-LET radiations at lower doses region has been formulated. Based on this parameter, the optimized effectiveness of high-LET radiations occurs while the energy of higher LET particles is deposited at spacing of 2 nm for linear primary ionizations.
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