An Analysis of CNS Tumors in Squash Preparations with Histological Correlation
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Background: Squash cytologyis now a well establishedand universally accepted techniquein diagnosing a wide range of CNS lesions and is currently employed for both therapeutic and prognostic reasons. Aims and Objectives: This study was conducted with an aim to correlate squash smears with histopathology and to compare statistical data employing sensitivity, specificity and diagnostic accuracy of squash cytology. The study also aims to find the pitfalls and limitations of Squash technique. Materials and Methods: An analysis of 100 brain tumour was done by squash preparation with histopathological correlationto evaluate the usefulness of the procedure. Crush Cytology smears were stained by Rapid H&E. Histopathology smears were made from formalin fixed tissues sent separately and stained with H&E. Results: Out of 100 cases, complete correlation with the final diagnosis was achieved in82%. Diagnostic accuracy increased to 92% when cases of partial correlation due tograding deviations were included. The sensitivity and specificity of neuroepithelialtumours were 86.6% and 98.18% respectively. The positive predictive value was 97.5% and negative predictive value was 90%. 10% partial correlation defect was not significant to affect the management of patient. Conclusion: The study shows it is possible to make correct diagnosis by squash preparation in 92% of the cases. The diagnostic yield is very high when the technique is combined withhistopathology. Itmaybe used as auseful adjunct to conventional histopathology.
Authors and Affiliations
Dr. Teleflo Boopathy, Dr. V. Karthika
Keywords
Related Articles
- EP ID EP589514
- DOI 10.9790/0853-1601078186
- Views 67
- Downloads 0
Effects of Smoking on Periodontium
Periodontitis is second most common cause of tooth loss in developed countries.[1 ] Many cross-sectional studies have proved that prevalence of periodontal disease is affected by smoking [2-4]Tobacco smoking, in the form...
Perianal Abscess with Fistula inAno Complicating As Basal Cell Carcinoma- A Rare Presentation
Fistula In Ano Usually Presents With Pus Discharge Perianal Region, Sometimes With Mucus Discharge. Malignant Transformation In Fistula In Ano Very Rare Presentation1 , And To Assess Preoperatively Is Almost Next To Impo...
Effect of Essential Phospholipids and Statin on Non Alcoholic Fatty Liver Disease in Rats Induced Periodontitis
NAFLD is the most common form of chronic liver disease, it is the hepatic manifestation of metabolic syndrome. Periodontal disease may helpfully increase the risk of progression from NAFL to NASH. Effective strategies ar...
Role of Low Molecular Weight Heparin in Treatment of Acute Pancreatitis in CMCH, Coimbatore.
AIM To study the effect of low molecular weight heparin in the treatment of acute pancreatitis. METHODOLOGY Patients presenting to emergency room of Coimbatore medical college hospital with features of acute pancreatitis...
A Comparitive study of Morbidity and Mortality in Enteric perforation between Primary repair and Primary Ileostomy with delayed closure
Perforation peritonitis is one of the most common surgical emergency in India and one of its main cause is Typhoid caused by bacterium Salmonella typhi. The spread of infection is usually by faeco-oral route. In underdev...