An analysis of risk factors for Multidrug Resistant Tuberculosis (MDR-TB): a hospital-based study
Journal Title: Journal of Public Health and Development - Year 2023, Vol 21, Issue 2
Abstract
Multidrug Resistant Tuberculosis (MDR-TB) is the world's most serious problem and one of the leading causes of death. Because of its difficult diagnosis, high rates of treatment failure, and death, MDR-TB is a new challenge in TB control programs. The study aims to identify and analyze the risk factors of Multidrug Resistant Tuberculosis (MDR-TB). The study used a case control study design and was conducted at the Labuang Baji Hospital in Makassar City, Indonesia. The sample was 140 people consisting of 70 in the case group and 70 in the control group. Purposive sampling was used to collect the data. Data were analyzed using STATA program with Multiple Logistic Regression. Significant risk factors of Multidrug Resistant Tuberculosis (MDR-TB) were duration of treatment (OR= 5.655 [Cl 95%: 2.507-12.999]; p<0.001), previous treatment history (OR= 4.833 [Cl 95%: 2.092-11.525]; p<0.001), PMO factor (OR= 3.106 [Cl 95%: 1.227-8.338]; p=0.008), compliance with drugs (OR= 10.961 [Cl 95%: 4.640-26.40]; p<0.001), drug side effects (OR=2.521 [Cl 95%: 1.070-6.126]; p=0.020) and protective factor is the complexity of drug regimen (OR= 0.329 [Cl 95%: 0.136-0.768]; p=0.005). It can be concluded that compliance with drugs is a dominant risk factor for MDR-TB. Improved TB control programs by monitoring the treatment of patients who experienced treatment failure (dropout) probably will increase treatment adherence and cut off MDR-TB transmission.
Authors and Affiliations
Sri Wahyuningsih, Andi Zulkifli, A. Arsunan Arsin, Ansariadi, Sudirman Nasir, Masyita Muis, Andi Agus Mumang
Keywords
Related Articles
- EP ID EP718602
- DOI 10.55131/jphd/2023/210208
- Views 49
- Downloads 0
Performance motivation and Dhammanamai health literacy according to Thai traditional medicine among village health volunteers in Uthaithani province
This cross-sectional study aimed to explain levels of Dhammanamai health literacy, investigate relevant factors, and identify the predicting factors of Dhammanamaihealth literacy according to Thai traditional medicine am...
Development of a hot weather warning tool for heat index monitoring in Thailand
This study aims to develop and test an extremely hot weather warning tool. The tool consists of a Node MCU ESP8266 microcontroller, air temperature and relative humidity sensor (DHT22), real time clock module (DS3231), m...
Comparison between using an Automatic Uterine Massage Machine and manual uterine massage on postpartum blood loss within two hours after delivery at labour room, Phramongkutklao Hospital
This experimental study compares the effectiveness of Automatic Uterine Massage Machine (AUMM) and Manual Uterine Massage on uterine contraction intensity and the amount of postpartum blood loss within two hours after de...
Practices, knowledge, and attitude toward dispensing antibiotics without a prescription in Iraqi pharmacies
Dispensing antibiotics without a prescription (DAWRx) is a potential threat to global public health and can lead to antimicrobial abuse and resistance development. Further research is required to examine the characterist...
The effect of personal initiative behavior on the performance excellence behaviors of patient unit nurse managers at international private hospitals in Thailand
Personal initiative behavior (PIB) is a major concept with effects on the performance of patient unit nurse managers in modern nursing organizations. PIB affects the performance excellence behavior (PEB) of individuals a...