An analytic comparative study about the antimicrobial activity of different generic and branded Amikacin on Escherichia coli - an In-vitro study
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 2
Abstract
A Generic drug is a pharmaceutical product usually intended to be interchangeable with an innovator product that is manufactured without any license from the innovator company and marketed after the expiry date of the patent or other exclusive rights. The generic drug can be equivalent to branded formulations if they have the same pharmaceutical form, therapeutic indications and similar bioequivalence [20%]. There is an increased report of adverse events against the active drug ingredient of the generic drugs. Many of these factors lead to the increased confusion in the medical field on prescribing drugs. The antimicrobial resistance is a global problem, probably due to the indiscriminate and irrational use of antibiotics, prescriptions for incorrect medicines or incorrect determinations of dose, route and/or duration [16]. Antibiotics are type of antimicrobial drugs used in the treatment and prevention of bacterial infections. There is increased incidence of resistance against many antibiotics which contributes to the serious emerging and re emerging infections. In this study the antibacterial activities of different generic and branded amikacin were compared against escherichia coli -In vitro.
Authors and Affiliations
M SaravanaKumar
Keywords
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