Postoperative wound infections and their antimicrobial susceptibility pattern in a tertiary care hospital in salem, India.
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2014, Vol 3, Issue 1
Abstract
Background: Surgical site infection (SSI) is defined as an infection that occurs at an incision site within 30 days after surgery. Postoperative wound infections have been an important cause of morbidity and cost burden for the patients. Aim & Objectives: To isolate and identify the bacteria causing postoperative wound infections and to determine the antimicrobial susceptibility pattern. Materials & Methods: One hundred and ten pus samples and wound swabs were collected from clinically suspected post-operative wound infection in Vinayaka Mission’s Kirupanada Variyar Medical College and Hospital, Salem from November 2011 to October 2012. The samples were processed as per standard guidelines. Antimicrobial susceptibility testing was performed as per CLSI guidelines. Results: Out of 110 pus samples and wound swabs, 41 samples (37.27%) were culture positive, out of which 5 samples showed more than 1 isolate. Sixty nine samples (62.72%) were culture negative. The common organisms isolated were Staphylococcus aureus 18(39.13%), Escherichia coli 10(21.73%), Klebsiella pneumoniae 8(17.39%) and Pseudomonas aeruginosa 7(15.21%). Most of the Staphylococcus aureus exhibited resistance to cefoxitin, cefazolin and gram negative bacilli showed resistance commonly to first and second generation cephalosporins. Conclusion: Staphylococcus aureus was the most frequently isolated pathogen from post- operative wound infections. Antibiotic susceptibility pattern of various isolates help to assist the clinician in appropriate selection of empirical antibiotics especially against hospital acquired infections.
Authors and Affiliations
J. Lalithambigai J. Lalithambigai
Keywords
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