In-vitro Antioxidant studies on ethanolic extracts of Boswellia ovalifoliolata and Saccharum spontaneum by DPPH, Nitric oxide and Lipid peroxidation methods.
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2013, Vol 2, Issue 1
Abstract
Oxidative stress is currently suggested a mechanism underlying various degenerative disorders such as atherosclerosis, cancer, aging, diabetes and Alzheimer’s. Chemical principles from nature such as flavonoids and other phenolic compounds were reported to act as scavengers of free radicals that are continuously generated in the human body. The aim of the present study was to investigate the antioxidant properties of ethanolic extracts of Boswellia ovalifoliolata and Saccharum spontaneum. The antioxidant properties of the extracts were determined by scavenging 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH), Nitric oxide (NO) and lipid peroxidation (LPO). The results of in-vitro studies showed higher percentage of inhibition of free radicals by ethanolic extract of Boswellia ovalifoliolata and saccharum spontaneum in a concentration dependent manner. The antioxidant effect may be attributed to the presence of phenolic compounds in the extracts which were quantified by Folin-ciocalteau method. From the results obtained, it may be concluded that Boswellia ovalifoliolata and Saccharum spontaneum possess significant antioxidant activities.
Authors and Affiliations
Geetha Kodali
Keywords
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