An assessment of clinical importance of low libido in the evaluation of men with late-onset hypogonadism
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 11
Abstract
<b>Aim. </b>We evaluated the relationship between total testosterone levels, libido and erecrile functions (ED) among men with sexual dysfunction and late-onset hypogonadism (LOH).<br><b>Material and methods.</b> 334 men over 50 years with LOH and sexual dysfunctions (low libido and/or ED) were invited to complete the International Index of Erectile Function questionnaire (IIEF-5), as a diagnostic tool for ED and libido was assessed using modified the Brief Sexual Function Inventory questionnaire (BSFI). Serum total testosterone (TT) were measured. Linear regresion model were used to analyze the factors that are associated with sexual dysfunctions and testosterone levels.<br><b>Results.</b> Mean patient age was 64 ± 9.2 years (range 50 to 78). Of the men 51% had low, 37% moderate and 12% high libido. Mean serum total testosterone levels among men with low, moderate and high libido were 2.4, 2.9 and 3.3 ng/mL respectively, and differences among means were statistically significant (p < 0.01). There was significant inverse relationship between BSFI score and total testosterone (r = -0.3481, p < 0.05) and BSFI score and age (r = -3382, p < 0.02). Moreover, there was significant inverse relationship between IIEF-5 score and total testosterone (r = -0.3123, p < 0.002) and IIEF-5 score and age (r = -0.3463, p < 0.02). These relationships were significant after adjustment for age and BMI.<br><b>Conclusions.</b> Erectile dysfunctions are more specific symptom of late-onset hypogonadism than low libido and correlated negatively with testosterone levels. Total testosterone level is an inadequate measure of sexual dysfunctions in men over 50 years.
Authors and Affiliations
Michał Rabijewski, Lucyna Papierska, Jarosław Kozakowski, Wojciech Zgliczyński
Keywords
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