An Association of Serum Vitamin D3, ionized calcium with Depression among teenagers.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Background and Objectives: The association of Vitamin D with depression is suggested due to the pressure of vitamin D receptors in cingulate cortex, thalamus, cerebellum, substantia nigra, amygdala and hippocampus. Depression is a mood disorder affecting approximately 1-6% of teenagers. This study aims at evaluating the association of serum vitamin D3, ionised calcium and depression among teenagers. Material and Methods:The study included 142 teenage children who visited the hospital for regular health checkup. They were evaluated by the questionnaire, “Depression scale for children”, serum vitamin D3 and ionised calcium was estimated. A comparison of socioeconomic data, serum vitamin D3, and ionised calcium was done. Observations:Out of 142 teenagers 36 children (25.6%) were diagnosed of suffering from depression. A significant negative correlation was observed between serum vit D3 and depression (r = 0.868, p = 0.05). Conclusion:An association of decreased vit D3 with depression was found in depression among teenagers. Hence vit D3 supplementation is required during growth years is essential along with preventive measures of depression.
Authors and Affiliations
Roma Rattan, Mihir Ranjan Nayak, Deepak Kumar Rout, Manaswini Dash
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