A Prospective Study of Bacteriological Profile of Bile in Patients with Biliary Stones
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
INTRODUCTION: Cholelithiasis is the most common digestive tract disorder. Treatment of acute episodes requires antibiotics. But pathogens and sensitivity of the pathogens to antibiotics vary widely. Bacteriological profile helps to prevent bacterial septicaemia. This study was conducted to study the frequency of bacterial growth in bile samples from patients undergoing surgery for bile stones, identify the common microorganisms which are found in the bile samples from patients undergoing surgery for bile stones& to analyze the antibiotic sensitivity pattern of the microorganisms cultured. METHODS: prospective study in a sample of 60 patients with cholecystitis who underwent cholecystectomy from June 2015 to august 2016.a structured questionnaire was used to collect patient details and symptoms. Microbiological and radiological investigations were done.Intraoperatively bile was collected and culture &sensitivity testing was done. Results were analysed using SPSS software. RESULTS: majority of the patients were elderly female with abdominal pain as presenting symptom and tenderness in right hypochondrium as major clinical sign.21% of the sample was culture positive with gram negative enterobactericiae as major organism and maximum sensitivity to aminoglycosides. CONCLUSION: Culture of the bile showed gram negative enterobacteriaeceae mainly klebsiella and E.coli.These bacteriae were sensitive to Aminoglycosides & other broad spectrum antibiotics.
Authors and Affiliations
Dr. S. Sreedevi M. S. , Dr. C. Rajasekaran M. S. , Dr. Jitesh M. S.
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