AN IN VITRO ANTIMICROBIAL POTENTIAL OF VARIOUS EXTRACTS OF COMMIPHORA MYRRHA
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2015, Vol 4, Issue 2
Abstract
Objectives: The aim of this study was to evaluate the antimicrobial activity of various extracts of the medicinal plant Commiphora myrrha. Methods: The agar well diffusion technique was followed to perform the antimicrobial activity of the candidate extracts against Gram- positive bacteria (Bacillus subtilis, Staphylococcus aureus), Gram- negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa), and two fungal species (Candida albicans, Apergillus Niger). Results: Methanolic and aqueous extracts of the resin of Commiphora myrrhaat concentration of 100 mg/ml was found to be more active against Gram- negative bacteria (Proteus vulgaris; Klebsiella pneumoniae; Escherichia coli and Pseudomonas aeruginosa) and Gram- positive bacteria (Bacillus subitilis), and also showed high antifungal activity against (Candida albicans and Aspergillus niger). While chloroform extract of the resin showed moderate activity towards Gram- positive and Gram- negative bacteria ,as well as against Candida albicans, whereas the same extract revealed high antifungal activity against Apergillus Niger. Conclusion: Methanolic, chloroform and aqueous extracts of Commiphora myrrha resin revealed that the selected entire plant had a significant potential effect capable to inhibit the growth of both bacterial and fungal standard species.
Authors and Affiliations
Abd-Ulgadir K S| Department of Microbiology, Faculty of Nursing Science, OIU., El Tahir A S| Department of Botany, Faculty of Science and Technology, OIU., AhmedH H| Department of Botany, Faculty of Science and Technology, OIU., El Shiekh H E| Department of Botany, Faculty of Science and Technology, OIU., Rakaz M A| Department of Botany, Faculty of Science and Technology, OIU., Abosalif KO| Department of Medical Parasitology & Medical Entomology, Faculty of Medical Laboratory Science, OIU., Abdelsalam KA| College of Applied Medical Sciences, Shaqra University - KSA., Satti AB| Department of Medical Parasitology & Medical Entomology, Faculty of Medical Laboratory Science, OIU.
Keywords
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