AN OVERVIEW OF CATARACT ACTIVITY AND THEIR SCREENING METHODS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2018, Vol 8, Issue
Abstract
A cataract is a clouding of the lens in the eyes which leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Cataracts are the cause of half of the blindness and 33% of visual impairement worldwide. Cataract is a multifactorial disease associated with several risk factors such as aging, diabetes, malnutrition, diarrhoea, poverty, sunlight, smoking, hypertension and renal failure. Various convenient models are available for the evaluation of drugs for the prevention of cataract formation they are galactose induced cataracts in rats, naphthalene induced cataracts in rats, selenite induced cataract in rats etc. Various medicinal plants having anti-cataract activity were reported with minimal adverse effects. Even there is the need to find out novel drug with minimal adverse effects to treat the cataract activity and to prevent the blindness in humans.
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