An overview of the biological function of curcumin in the processes of oxidative stress, inflammation, nervous system, and lipid levels
Journal Title: Central Asian Journal of Medical and Pharmaceutical Sciences Innovation - Year 2023, Vol 3, Issue 1
Abstract
Recently, treatment with antioxidants, especially herbal therapy, has been widely studied to prevent the occurrence of many diseases. Turmeric with the scientific name Curcuma longa from the Zingiberaceae family is one of the oldest plants that have been applied in traditional medicine. It has been abundant and it has been used to protect many tissues from different damage. Many researches have been reported on curcumin's antioxidant, anti-cancer and anti-inflammatory, features. Curcumin clearly shows antioxidant and free radical scavenging effects in vivo and in vitro conditions. This compound can protect normal cells from the attack of reactive oxygen species by neutralizing oxidative damage. The anti-inflammatory impacts of curcumin have been established in numerous researches via different pathways. Curcumin directly binds to small beta-amyloids and prevents the accumulation and formation of fibrils in vitro and in vivo. Thus it can be the cause of its effect in Alzheimer's disease. Curcumin significantly reduces the level of LDL and VLDL in the plasma and causes a decrease in the total level of cholesterol in the liver. In this study, we intend to describe the biological features of curcumin as a natural substance in processes such as oxidative stress, inflammation, nervous system, and lipid levels.
Authors and Affiliations
Antoni Sureda; Silvia Tejada; Usman Mir Khan; Zeliha Selamoglu
Keywords
Related Articles
- EP ID EP714400
- DOI 10.22034/CAJMPSI.2023.01.01
- Views 66
- Downloads 0
The role of molecular factors in gestational hypertension and the pathogenesis of preeclampsia
Preeclampsia (PE) is classified as a systemic condition that generally develops with high blood pressure and protein excretion in pregnant women after 20 weeks. This condition is characterised by inadequate placental blo...
Study of A1298C variation in MTHFR gene as a molecular risk factor for male infertility in Iran
Methylenetetrahydrofolate reductase is an important enzyme in folate metabolism pathway. There are some studSome studies investigateding the correlation of a common gene variation (A1298C) with male infertility in a spec...
The vital function of physical activity, exercise, and diet in the management of COVID-19 Symptoms
The COVID-19 pandemic has caused many of us to stay constantly hospitalized and isolated. In addition, this has severe long-term mental health impacts such as depression, post-traumatic stress, anxiety, rage, anger, and...
The physiology of vitamin D and its involvement in cardiovascular diseases
Cardiovascular diseases (CVD) is a leading reason of global mortality. The most common causes of CVD-related deaths are ischemic heart disease, congestive heart failure, and stroke. Cardiac ischemia is correlated with co...
Description of schizophrenia and related mechanisms: oxidative stress and role of ketamine against N-methyl-D-aspartate receptor
Schizophrenia is a very violent mental illness with an occurrence of less than 1% in the global population. The disease mainly happens in early adulthood and late adolescence, at which time the symptoms and psychological...