The crucial role of estrogen/androgen hormones and their receptors in male infertility risk
Journal Title: Central Asian Journal of Medical and Pharmaceutical Sciences Innovation - Year 2021, Vol 1, Issue 1
Abstract
Steroid hormones, including androgen and estrogen, regulate gene transcription in several tissues, especially in reproductive systems. It has been shown that the two these mentioned hormones are vital for the regulation of spermatozoa released from the epithelialum cells in of seminiferous tubes, a procedure which is characterized by endocytosis and broad regeneration of actin filaments. A subgroup of sterile men displayeds decreased levels of testosterone and elevated concentrations of estrogen., neverthelessNevertheless, it is undecided how increased levels of estrogen could promotes worsening ofdecrease male fertility potential. Though the molecular origin for estrogen-induced worseningdecreased male fertility levels of male fertility remains vague, estrogen receptors (ERs) have an essential role in facilitating this procedure. In addition, the androgen hormone plays an important role in the male reproductive system. They action act through their receptors, the androgen receptor (AR). It has been reported that AR mutations could result in idiopathic male infertility. In this review, the role of estrogen and androgen hormones and their receptors in male infertility, have beenwere discussed.
Authors and Affiliations
Paola A. Rivera-Diaz; Claudia Patricia Ortiz; Daniel Ricardo Delgado
Keywords
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- EP ID EP714123
- DOI 10.22034/CAJMPSI.2021.01.06
- Views 87
- Downloads 0
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