An unusual presentation of a case of primary plasma cell leukaemia in a psychotic patient with associated tuberculosis
Journal Title: The Indian Practitioner - Year 2015, Vol 68, Issue 1
Abstract
Plasma cell leukaemia (PCL) is a rare disorder that can develop spontaneously (primary) or evolve in patients with multiple myeloma (secondary). Histogenetically, plasma cell leukaemia is derived from terminally differentiated B cells. It is diagnosed by the presence of absolute plasma cell count > 2000/ cumm or > 20% circulating plasma cells in blood. We report a rare case of primary plasma cell leukaemia in a patient of bipolar affective disorder presenting with weakness of lower limbs, fatigability, generalized myalgia and mood changes. She was a known case of pulmonary tuberculosis. There was no previous history of multiple myeloma. Clinical spectrum, cytomorphological features and prognosis of PCL are discussed.
Authors and Affiliations
Anshu Gupta, G Chhavi, K Anju
Phenylketonuria and Mental Retardation An urgent need for availability of therapeutic diet at National Level
PKU is an autosomal recessive inborn error of amino acid metabolism (IEM) and the classic PKU disorder is characterised by a deficiency in phenylalanine hydroxylase (PAH) enzyme which is responsible for intellectual disa...
Inclusion Cyst in a Neonate
Paramesonephric cysts are very rare, so are not suspected, leading to delay in diagnosis causing irreversible renal damage. Reports of bigger cysts, upto 8-10 cms are seen in adults. Timely intervention helps in preventi...
Management of Cardiac Arrest in Emergency Department
Sudden Cardiac Arrest remains a leading cause of death worldwide. Excellent cardiopulmonary resuscitation (CPR) and early defibrillation for treatable arrhythmias remain the cornerstones of BLS and ACLS. The “mantra” is:...
Spirometric Norms in Healthy Adults of Ahmednagar District of Maharashtra
CONTEXT: Pulmonary function test (PFT) is an invaluable tool for assessment of lung function and is also the investigation of choice for overall assessment of respiratory function. Though its application in diagnosis and...
Renal dysfunction secondary to tuberculosis: A case report
.