An Unusual Presentation of Systemic Lupus Erythematosus with Vasculitic Polyneuropathy
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 11
Abstract
We report a case of systemic lupus erythematosus (SLE), in a 48-year-old woman, a known hypertensive and recently diagnosed diabetic, with a predominant complain of acute onset bilateral lower limb weakness and loss of sensation of the bilateral palm and soles with bowel incontinence and excessive hair loss. On evaluation, her vitals were stable, cardiovascular, respiratory, and abdominal systemic examination revealed no significant abnormality. Neurological examination revealed a normal tone with distal muscle weakness more in the lower limb than in the upper limb. She was thoroughly evaluated for the above-mentioned complaints and examination findings. Nerve conduction study was done - which revealed upper limb - severe asymmetric motor sensory neuropathy - axonal type and lower limb - axonal symmetrical severe polyradiculoneuropathy. Nerve biopsy revealed a vasculitic neuropathy. Autoimmune workup was positive for antinuclear antibodies, and low C3 levels, with direct Coombs test positive, increased UPCR ratio. According to the Systemic Lupus International Collaborating Clinic criteria, she was diagnosed with SLE. Hence, this is a case of SLE, with a primary presentation of a vasculitic neuropathy, an unusual occurrence.
Authors and Affiliations
Shruthi Muralidharan, K Arun, Subramaniyan Kumarasamy, v Ruckmani
Keywords
Related Articles
- EP ID EP484059
- DOI -
- Views 141
- Downloads 0
A Gender-based Comparative Study of Visual and Auditory Reaction Time on 1st Year Medical Students “Before” and “After” Caffeine Intake
Introduction: The present study is a gender-based comparison of the auditory and visual reaction time (RT) in male and female 1st year medical students, before and after the administration of caffeine present in coffee....
A Prospective Clinical Study on Types and Diagnostic Criteria of Fungal Rhinosinusitis used in Tertiary Teaching Hospital of Telangana
Background: Fungal rhinosinusitis (FRS) is a disease of a wide spectrum of immune and pathological responses and includes invasive, chronic, granulomatous, and allergic variants. Consensus on its terminology, pathogenesi...
Study on Cardiovascular Autonomic Function Tests on Young Healthy Males and Females
Background: Autonomic neuropathy is a common complication of several systemic disorders like diabetes mellitus. To combat that its early detection is essential. However, to understand the pathophysiological states, there...
Clinico-pathological Study of Pancytopenia: A Prospective Study
Background and Objectives: Pancytopenia is an important hematological entity. It is a disorder in which all three major formed elements of blood are decreased in number. The present study has been undertaken to find out...
Role of High-Resolution Computed tomography in the Evaluation of Pulmonary Metastases: A Tertiary Hospital-Based Study
Background: Pulmonary metastases constitute 20–54% of extrathoracic malignancies occurring all over the world. Twenty percent of metastatic disease is isolated to the lungs. Development of lung metastases indicates disse...