Analysis and characterization of cefixime by using IR, HPLC and gas chromatography
Journal Title: International Journal of Pharmaceutical Chemistry and Analysis - Year 2018, Vol 5, Issue 2
Abstract
To develop a new simple sensitive accurate and economical analytical methods for the estimation of related compounds in Cefixime formulations Validate the proposed methods in accordance with USP EUROPE and ICH guidelines for the intended analytical application Identify whether the given sample is Cefixime by IR spectroscopy and solubility test To determine the wavenumber in cm1 reciprocal to wave length region of given sample by Infrared Spectroscopy To determine the moisture content present in the given sample of Cefixime by Karl Fischer method Find out the assay and related substances impurities of given Cefixime by using the validated method with help of High performance Liquid Chromatography Estimate the amount of Residual solvents by Gas Chromatography The tests were performed as per the requirements of EUROPE monograph for CefiximeKeywords Cefixime IR HPLC and gas chromatography
Authors and Affiliations
M. Prasada Rao, B. Rama Rao, M. Srikanth
Keywords
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- EP ID EP481438
- DOI 10.18231/2394-2797.2018.0012
- Views 82
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