Burn wound healing potentials of Cynodon dactylon (L.) Pers.
Journal Title: International Journal of Pharmaceutical Chemistry and Analysis - Year 2018, Vol 5, Issue 3
Abstract
In this study the hydroalcoholic extract of the plant Cynodon dactylon L Pers was undertaken to evaluate the wound healing property on Burn Wound Model and to compare the effect of the combination of hydroalcoholic extract ofCynodon dactylon L Persand Silver Sulphadiazine with Silver Sulphadiazine alone Six groups are made and each group consist of 6 animals in it Each animal of all the six group is inflicted with partial thickness burn wound The group is numbered as Group I to Group VI The animals in Group I are taken as control where no drug is given to them To the Group II animals Standard silver sulphasalazine is given In case of group III animals they are subjected to hydroalcoholic extract of Cynodon dactylon Animals in Group IV and Group V received pure ethanolic extract and aqueous extract respectively In case of Group VI animal they are treated with standard drug as well as extract The study mainly focuses on observing parameters like period of epithelialization and the wound contraction percentage It is observed that the animals in the group which received both hydro alcoholic extract and sulphadiazine showed an improved burn wound contraction In addition to it the group IV and V shows a decreased epithelialization period Keywords Cynodon dactylon L Pers Epithelialization hydroalcoholic extract HAE Silver Sulphadiazine Wound contraction
Authors and Affiliations
Koushlesh Mishra, Anand Kumar, Anil K. Sahu, Pankaj Kashyap, Saraswati P. Mishra
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