Analysis of enterovirus serotype results in Dapeng New District， Shenzhen from 2016 to 2022
Journal Title: Shanghai Journal of Preventive Medicine - Year 2024, Vol 36, Issue 6
Abstract
Objective To provide a basis for human enteroviruses prevention and control by monitoring the enterovirus （EV） and its main virus types.Methods Samples of hand-foot-and-mouth disease， herpetic angina and fever clinic patients in Dapeng New District of Shenzhen from 2016 to 2022 were tested for EV with real-time polymerase chain reaction （PCR）. To identify the isolates of EV， VP1 genes of EV were amplified with nested reverse transcription PCR， and then sequenced.A geneticphylogenetic tree was constructed based on the VP1 gene.Results Among the 1 124 suspected hand-foot-and-mouth disease cases， 740 （65.84%） tested EV positive. Coxsackievirus A6 （CVA6） and Coxsackievirus A16 （CVA16） were the main two serotypes with regular cycle trends. Of the 137 suspected herpetic angina cases， 88 （64.23%） were EV positive， with Coxsackievirus A4 （CVA4） and CVA16 as the dominant serotypes. Among 428 respiratory infection specimens， 71 （16.59%） were EV positive. Coxsackievirus A4 （CVA4） was the predominant serotype which caused herpetic angina and respiratory infection. The epidemic EV isolates CVA6 from Shenzhen had a close genetic relationship with isolates in China’s mainland.Conclusion The main serotypes EV CVA6 and CVA16 which caused hand-foot-and-mouth disease exhibit cyclical trends. The risk of EV transmitted from abroad is low， but their genetic variation and virulence change should be monitored continuously. In addition， the monitoring of dominant isolates CVA4 which cause herpetic angina and respiratory infection should be strengthened.
Authors and Affiliations
LIAN Xianqiang,LIU Jianji,WANG Wenxiang,
Keywords
Related Articles
- EP ID EP741910
- DOI -
- Views 12
- Downloads 0
Comparative analysis of Aedes albopictus surveillance index in Yangpu District, Shanghai
Objective To analyze the interannual fluctuation， seasonal fluctuation， habitat distribution and the correlation of the 3 monitoring indicators of Aedes albopictus in Yangpu District of Shanghai from 2017 to 2021， and...
Analysis of cerebrovascular disease between 1996 and 2021 in Minhang District of Shanghai
ObjectiveTo analyze the changing trend of cerebrovascular disease burden in Minhang District of Shanghai from 1996 to 2021ï¼ and to provide scientific evidence for government to formulate targeted cerebrovascular diseas...
Influence of family smoking on children’s exposure to second-hand smoke in rural Taizhou City
<b>Objective:To analyze the household smoking behavior of smokers in rural Taizhou City of Zhejiang Province， and to provide the basis for the intervention measures to reduce children's second-hand smoke （SHS） exposur...
Effects of different feeding patterns on physical and nutritional status of infants aged 6â12 months
ObjectiveTo analyze the effects of different feeding patterns on the physical and nutritional status of children aged 6â12 monthsï¼ so as to provide reference for promoting scientific feeding and health development of...
Expert consensus on COVID-19 vaccination for children with special medical conditions
Children with certain comorbidities and immunocompromising conditions are highly vulnerable to SARS-CoV-2 infection. Vaccination against SARS-CoV-2 is an important strategy to reduce deathï¼ critical illness and overall...