Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 7
Abstract
ObjectiveTo explore the effect of paliperidone palmitate treatment on schizophrenic patients in the community.Methods446 schizophrenic patients who used paliperidone palmitate injection were selected in Shanghai. Before and after the treatmentï¼ the disease family burden scaleï¼ the concise evaluation scale of drug treatment complianceï¼ the VAS100 score of treatment satisfactionï¼ the short form of quality of life measurement scaleï¼ and the screening scale of social function defects were used to evaluate the effects of paliperidone palmitate injection. The data were statistically analyzed using SPSS 26.0 software.ResultsAfter using paliperidone palmitate injectionï¼ the total score of family burden ï¼13.94±12.17ï¼ï¼ the score of daily family activities ï¼3.26±2.74ï¼ï¼ the score of family entertainment activities ï¼2.21±2.30ï¼ï¼ and the score of family relationship ï¼2.79±2.76ï¼ were significantly higher than those before the treatment ï¼14.98±12.64ï¼ 3.51±2.88ï¼ 2.48±2.38ï¼ 3.11±2.87ï¼ respectivelyï¼ all with P<0.05ï¼. The scores of the World Health Organization on quality of life brief scale ï¼62.89±11.94ï¼ and the medication compliance scale ï¼28.11±5.64ï¼ were better than those before treatment ï¼60.67±12.62 and 27.37±6.96ï¼ all with P<0.05ï¼. Compared with the prior treatment without paliperidone palmitate injectionï¼ the number of readmissions after treatment was significantly reduced ï¼P<0.01ï¼.ConclusionThe treatment of paliperidone palmitate injection has significant effectï¼ which can effectively reduce the disease family burden of Schizophrenic patientsï¼ improve their quality of lifeï¼ enhance their drug complianceï¼ reduce the readmission rate of patientsï¼ ensure long-term treatment effect and promote disease recovery.
Authors and Affiliations
GE Xiaolei,ZHANG Weibo,CHEN Chunmei,HE Siyuan,ZHAO Miaomiao,JIN Jin,XIE Bin,CAI Jun,ZHU Yi,
Keywords
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