Analysis of metastatic bone disease in a tertiary care centre
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
Introduction Metastasis to the bone is the third commonest site next to lung and liver It is one of the leading cause of morbidity and mortality in the world being an important prognostic indicator in advanced cancers The axial skeleton is more commonly involved than the appendicular skeleton due to the venous blood flow through the bat sons plexus Commonest site involved are the spine femur pelvis skullMaterials and Methods A retrospective analysis of cases with metastatic bone disease confirmed by histopathology and followed by immunohistochemistry was carried out in the department of Pathology SRMC from January 2014 to December 2016 The data of same were analyzed and recordedResults A total of 36 cases with bone metastasis were analyzed of which 26 patients were males and 10 were females Metastasis from epithelial tumors were 94 as compared to 6 of deposits from mesenchymal tumor Most common site of involvement was the spine 50 second most common being femur 25 followed by the iliac bone 14 and clavicle 3 tibia 3 skull 3 radius 3 in both males and females Most common primary site of origin were the Lung 29 followed by prostate 17 Gastrointestinal tract 14 renal 11 breast 6 thyroid 6 ovary 3 penis 3 liver 3 Thigh soft tissue 3 and uterus 3 For 3 cases 8 the primary site was unknownConclusion Patients presenting with metastatic bone disease is increasing over time but advancement in treatment and awareness among patients have helped in early detection and prompt treatment and longer survivalKeywords Metastasis Bone Primary Immunohistochemistry
Authors and Affiliations
Subalakshmi . B, B. Nellaiyappan, J. Thanka
Keywords
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- EP ID EP475951
- DOI 10.18231/2394-6792.2018.0097
- Views 61
- Downloads 0
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