Cytological evaluation of lung mass FNA under Computed tomography guidance: A study of 123 cases
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Computed tomography (CT) guided Fine needle aspiration cytology (FNAC) is a simple, safer, and rapid technique. CT guidance can assist FNAC from any part of thorax without any major complications. FNAC helps distinguish between benign and malignant lesions and also effectively aids in morphological typing of lung cancer, thereby reducing the delay in initiation of specific therapy like chemotherapy or surgery. Materials and Method: One hundred and twenty three cases of lung mass lesions were evaluated with CT guided FNAC. Smears were stained with May-Grunwald Giemsa and Hemotoxylin & Eosin (H & E) stain for rapid cytopathological evaluation of the lesions. Results: Out of 123 cases included in the study, 90 cases (73.17%) were male and 33 (26.83%) were female. The mean age in malignant cases was 60.3 years whereas it was 50 years in benign lesions. Cytological examination showed that 109 cases were malignant and 14 cases were benign lesions. Cytomorphological diagnosis revealed maximum number of cases belonged to adenocarcinoma (60.9%). Rest of the cases were Squamous cell carcinoma (16.2%), Non-specific inflammation (4.8%), Granulomatous inflammation (3.2%), metastatic deposits (3.2%) and spindle cell neoplasm (1%). Only ten cases could be followed up for histopathological evaluation. All the cases confirmed the primary diagnosis of malignancy on histopathological examination. Conclusion: CT guided FNAC is a simple, and reliable for the diagnosis and sub typing of lung cancer, thereby reducing the delay in initiation of specific therapy like chemotherapy or surgery.
Authors and Affiliations
C. Nalinimohan, E. Jayashankar, Ashok Kumar D
Role of thoracoscopic pleural biopsy in evaluation of pleural effusion
Context Evaluation of a patient with pleural effusion involves clinical radiological and cytological evaluation of pleural fluid and histological evaluation of pleural biopsy It is not always possible to identify the exa...
Correlation of p63 protein expression and Ki-67 labelling index with histological grades of meningiomas: A five years study
Introduction Meningiomas account for 1325 of primary intracranial tumours and 25 of intraspinal tumors and histological grading has prognostic and therapeutic implications However histological criteria are sometimes not...
Histopathological study of neoplastic lesions of large intestine –A five year experience
Introduction Large intestine has a varied spectrum of lesions both nonneoplastic and neoplastic We took both a retrospective and prospective study in the Post Graduate Department of Pathology The clinical details were so...
Accuracy and reliability of Tzanck smear compared to histopathology in ulcerative and nodular lesions of Skin
Background: Though cytopathology was an excellent diagnostic tool in routine dermatologic practice, studies relating to histopathological and cytological correlation in relation to ulcerative and nodular lesions are few....
Evaluation of incidence of anemia in type 2 diabetic patients with normal renal function
Aim: The study was carried out over a period of 6 months to evaluate the incidence of anemia in Type 2 diabetic patients with normal renal functions. Methods: The study group comprised of 100 patients with TYPE 2 diabete...