Histopathological study of neoplastic lesions of large intestine –A five year experience
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
Introduction Large intestine has a varied spectrum of lesions both nonneoplastic and neoplastic We took both a retrospective and prospective study in the Post Graduate Department of Pathology The clinical details were sought out from the medical records and the specimens were collected from the patients diagnosed as colorectal carcinoma in the histopathology spectrum Intestinal tumors account for a large proportion of all neoplasms There is a significant geographical racial and ethnic variation in the incidence rate and pattern of colorectal carcinoma it is third most common cancer in men and second in women worldwideAims and Objectives 1 To study the neoplastic lesions of large intestine for a period of five years 2 To evaluate different histopathological types of tumors of colorectum 3 To correlate the various neoplastic lesions in relation to age sex family history and dietary habits of the patientMaterials and Methods A five year study from year December 2012 to December 2017 3 year retrospective and 2 years prospective study was carried out The necessary information and clinical data was obtained from the concerned sections It included 248 resected specimens of large intestineResults Out of 248 large intestine specimens 3065 ie 76 were nonneoplastic 621 ie 154 were neoplastic and 18 were inadequate biopsiesMalignant Neoplasm is more common than benign neoplasm in the colon Adenocarcinoma is the most common histological variant of colon carcinoma There is marked increase in the incidence of malignancies of colon hence the approach to early diagnosis by carrying out biopsies in clinically symptomatically suspicious patients should be the thumb rule for good managementKeywords Neoplasm Adenoma Adenocarcinoma Polyp Gastrointestinal stromal tumor
Authors and Affiliations
Aneeta Singh Malhotra, Archana Gupta, Sheikh Mahvesh, Anam Khurshied, Urvashi Andotra
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