ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF VILDAGLIPTIN IN BULK AND ITS DOSAGE FORM USING UV SPECTROPHOTOMETER
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
A simple, rapid, precise and economical Analytical method development has been developed for quantitative vildagliptin in manufactured tablet formulation. The stock solution and subsequent dilution of vildagliptin was done in 0.1% NaOH. Solution of vildagliptin in 0.1% NaOH showed absorption maxima at 216.00 nm. The drug obeyed Beers-Lamberts Law in the concentration range of 10-100 ?g/mL with Coefficient of correlation (R2) was 0.997. The standard the method can be adopted in routine analysis of vildagliptin in bulk and tablet dosage form.
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