Ankylosing Spondylitis (~ Amavata): A Case Study
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2018, Vol 0, Issue 0
Abstract
Ankylosing spondylitis (AS) is a multifaceted, potentially devastating disease that is insidious in onset, making progress to radiological sacroiliitis over several years. Patients with symptomatic AS drop productivity owing to work disability and redundancy has a considerable use of healthcare resources, and compact quality of life. The pathogenesis of AS is poorly understood. AS belongs to a group of rheumatic diseases known as the spondylo-arthropathies, which showsa strong connection with the hereditary marker HLA-B27.Immune mediated mechanisms involving human leucocyte antigen (HLA)-B27, inflammatory cellular infiltrates, cytokines, and genetic and environmental factors are considerable to have key roles. The detection of sacroiliitis by radiography, magnetic resonance imaging, or computed tomography in the presence of clinical manifestations is indicative for AS, although the presence of inflammatory back pain plus at least two other characteristic features of spondyloarthropathy (for example, enthesitis and uveitis) is highly predictive of early AS. Non-steroidal anti- inflammatory drugs (NSAIDs) plays the major role in the treatment of this situation; however, they have serious adverse effects and have limitations for an extended therapy. Hence, there is a need for drugs having good efficacy with low toxicity in this devastating disorder. From the Ayurvedic perspective, the disease can fall under amavata, which may be successfully managed when intervention is started in its early stages. The whole management includes Deepan, Pachan and Vatanuloman described in the chikitsa sutra of Amavata. Shamana treatment with aamavatari rasa, rasonpind, sanjeevanivati, rasnasaptakakwatha and Simhanadaguggulu has been found useful in restriction its progression. This article presents a solitary case report in which these treatments achieved significant success.
Authors and Affiliations
Rajesh Jain, K. S. Girhepunje, Anupam Srivastav, J. S. Tripathi
Keywords
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