ANTENATAL MAGNESIUM SULPHATE FOR NEUROPROTECTIONRECOMMENDATIONS & GAPS IN KNOWLEDGE
Journal Title: International Journal Of Advances In Gynaecology - Year 2017, Vol 1, Issue 3
Abstract
The main mechanism of neuroprotection action of magnesium is by acting as a cerebral vasodilator and blocking calcium mediated cell injury. Some studies suggest that magnesium sulphate decreases the production of free radicals and proinflammatory cytokines after ischemic insult. A study showed that neonates whose mothers received antenatal magnesium sulphate had higher cord levels of brain derived neurotrophic factor (BDNF), which has been shown to be protective against hypoxic brain injury in vivo.
Authors and Affiliations
Dr. Sankalp Dudeja, Dr. Japleen Kaur
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