HELICOBACTER PYLORI INFECTION IN AMNIOTIC FLUID MAY CAUSE HYPEREMESIS GRAVIDARUM
Journal Title: International Journal Of Advances In Gynaecology - Year 2019, Vol 3, Issue 4
Abstract
OBJECTIVES: Limited data are avaible from recent trials involving pregnant women to guide the diagnosis of Helicobacter pylori infection. There is no data about presence of H. pylori in the amniotic fluid as well. Furthermore, relation between amniotic fluid H. pylori and hyperemesis gravidarum (HG) has not been characterized yet. MATERIALS AND METHODS: Pregnant women undergoing amniocentesis were enrolled in the study. Presence of H. pylori in amniotic fluid was assessed by stool antigen test. A perinatalogist independently performed amniocentesis. Obtained amniotic fluid was sent to the laboratory to assess H. pylori infection by stool H. pylori antigen assay. We determined the rate of H. pylori in amniotic fluid and assessed relations between H. pylori infection and pregnancy outcome including HG. RESULTS: Between May 2017 - September 2017, we enrolled 48 pregnant women who underwent amniocentesis to detect possible fetal malformations. Among them, 28 (58.3%) were found to have positive for H. pylori in the amniotic fluid. The rate of HG was significantly higher (71.4%) in patients who tested positive for H. pylori in amniocentesis than H. pylori negative group (20%), (p<0.001). CONCLUSIONS: The main new finding of the study is that presence of H. pylori in the amniotic fluid is possible. Our data suggest that H. pylori infected amniotic fluid is associated with experience of past HG. Current study may have important implications for detecting HG and may help identify patients who would derive the most benefit from future preventive strategies.
Authors and Affiliations
Sasmaz MI, Dulger AC, Ayvaz MA, Demir B, Tolunay HE
Keywords
Related Articles
- EP ID EP649272
- DOI -
- Views 63
- Downloads 0
TO RULE OUT THE RISK OF DEVELOPING PIH WITH HIGH SERUM Β-HCG LEVELS IN EARLY PREGNANCY
Aim Of This Study Is To Test The Hypothesis That Women With High Serum Β-Hcg Levels In Early Pregnancy Are At Higher Risk Of Developing PIH (4). In This Study The Serum Β-Hcg Is Measured In 13th-20th Weeks Of Gestation O...
LEPTOSPIROSIS IN PREGNANCY: A MATERNAL NEAR MISS CASE
We report the case of a 21 year old primipara presenting with primary postpartum haemorrhage with features of hepatocellular jaundice, later diagnosed to be due to leptospirosis on serology. AFLP and HELLP syndrome being...
HELICOBACTER PYLORI INFECTION IN AMNIOTIC FLUID MAY CAUSE HYPEREMESIS GRAVIDARUM
OBJECTIVES: Limited data are avaible from recent trials involving pregnant women to guide the diagnosis of Helicobacter pylori infection. There is no data about presence of H. pylori in the amniotic fluid as well. Furthe...
KNOWLEDGE, ATTITUDE AND PRACTICE OF MOTHERS TOWARDS FEMALE GENITAL MUTILATION IN SOUTH WEST SHOA ZONE, OROMIA REGION, ETHIOPIA
Background: Female genital mutilation is a long held tradition in the society of Ethiopia. It has significant drawbacks leading women of all age to different forms of morbidity and mortality. Assessment of KAP of mothers...
IMPACT OF CHANGED NACO GUIDELINES ON HIV VERTICAL TRANSMISSION AT TERTIARY REFERRAL INSTITUTE IN MUMBAI
OBJECTIVE : To assess the impact of changed guidelines of National AIDS Control Program on vertical transmission at our centre. DESIGN: Retrospective analysis of outcomes of standard treatment as per revised national gui...