Anterior segment findings and systemic disease associations in scleritis
Journal Title: Medpulse International Journal of Ophthalmology - Year 2017, Vol 3, Issue 1
Abstract
Objectives: To evaluate Anterior segment findings and systemic disease associations in patients with scleritis and to assess any ocular or systemic prognostic significance of it. Materials and Methods: Patients with scleritis alone and patients with scleritis-associated peripheral keratopathy; attending our hospital during period of January 2011 to January 2015 were examined. Review of patients with scleritis and the different patterns of peripheral keratopathy: (peripheral corneal thinning, stromal keratitis, and peripheral ulcerative keratitis (PUK)), review of ocular and systemic outcomes were done and comparisons between patients with scleritis with and without peripheral keratopathy was done. Results: Patients with scleritis associated with Keratopathy had significantly more necrotizing scleritis (P<.05), decrease in vision ( P<.05), anterior uveitis ( P<.05), and potentially lethal specific-disease association ( P<.05) than did patients with scleritis alone. Patients with Peripheral keratopathy had the worst ocular and systemic outcomes. Of the 24 patients with Peripheral keratopathy 58% had necrotizing scleritis (P<0.05), virtually all had a potentially lethal systemic disease (P<0.05). Conclusion: The detection of peripheral keratopathy, and especially in a patient with scleritis indicates a poor ocular and systemic prognosis.
Authors and Affiliations
Girish Gadre, Vijay Karambalekar, Dhwanit Ketwani
Keywords
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