Anthropometric Indices, Inflammatory & Oxidative Stress Markers in Metabolic Syndrome
Journal Title: Scholars International Journal of Biochemistry - Year 2019, Vol 2, Issue 1
Abstract
The present study was undertaken to investigate the variations of anthropometric indices, inflammatory oxidative stress and anti-oxidant markers in subjects with metabolic syndrome (MetS) compared to their age & sex-matched controls, and to evaluate the correlations, if any of the anthropometric indices with the pro-oxidant state in subjects with MetS. One hundred and fifty-three subjects with MetS and one hundred and fifty-five controls were recruited for the study according to the NCEP ATP III (National cholesterol education program – Adult treatment panel III) criteria for MetS. Anthropometric characteristics of all subjects were recorded using clinical Proforma. Blood samples were collected after taking informed written consent from subjects. Plasma glucose, lipid profile analysis, malondialdehyde (MDA), total antioxidant capacity and C reactive protein (CRP) was estimated in all blood samples. This study clearly indicates that obesity measured by anthropometric measurements including BMI and WC were increased in MetS patients as compared to controls. Inflammatory marker CRP was found to be significantly high in patients with metabolic syndrome. The oxidative stress as assessed by serum MDA was significantly higher, whereas total antioxidant capacity (TAOC) was lower in MetS patients than that of age & sex matched controls.
Authors and Affiliations
Deepthy C Sahadevan, Busi Karunanand, D. K Sharma
Keywords
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