ANTI-CANCER ACTIVITY OF CEDRUS DEODARA IN 1,2-DIMETHLY HYDRAZINE (DMH) INDUCED ANTI CANCER MODEL IN RATS
Journal Title: Asian Journal Of Pharmaceutical Research and Development - Year 2018, Vol 6, Issue 2
Abstract
Cancer is a dangerous disease of all multicellular organisms. Cancer is a serious as well as life threatening disease characterized by uncontrolled division and growth of abnormal cells in the body. In present study anti cancer potential of traditional herbal Cedrus deodara were studiedin1,2-dimethly hydrazine (DMH) induced anti cancer model. Various biochemical parameters were evlautaed such as Alakaline phosphate, Aspartate aminotransferase, Alanine aminotransferase and Histology of Liver tissue were examined. Data of the study revealed that significant depletion of biochemical markers in DMH-untreated rats as compared with control rats throughout the experimental period. This depletion might because the extract treated group shows improvement levelin rats treated with DMH showed significant decrease, as a result levels of antioxidant enzymes decreased. Also DMH produces free radicals in blood, liver and the large intestine of experimental models
Authors and Affiliations
Amit Sharma
Keywords
Related Articles
- EP ID EP496373
- DOI 10.22270/ajprd.v6i2.348
- Views 130
- Downloads 0
EBOLA VIRUS: AN OVERVIEW
Ebola virus disease (EVD), also known as Ebola hemorrhagic fever (EHF) or simply Ebola, is a viral hemorrhagic fever of humans and other primates caused by ebola viruses. Signs and symptoms typically start between two da...
ANALYSIS OF PATENT TRENDS BETWEEN 2000 AND 2017 IN THE AREASOF MEDICAL, DENTAL AND TOILET PREPARATIONS INCLUDING OF PHARMACEUTICALS
Patent information is highly important for decision makers. Their demand for latest technology trend and competitor analysis poses new challenges with respect to the processing and visualization of large amount of patent...
REGULATORY ASPECTS OF CLEANING AND CLEANING VALIDATION IN ACTIVE PHARMACEUTICAL INGREDIENTS
Pharmaceutical product and active pharmaceutical ingredients (APIs) can be contaminated by other pharmaceutical products or APIs, by cleaning agents, by microorganisms or by other materials e.g....
AN EXTENDED REVIEW AND SUMMARY ON FACTS ABOUT ETIOLOGY EPIDEMIOLOGY CLINICAL DIAGNOSIS AND MANAGEMENT OF SCRUB TYPHUS INFECTION
Scrub typhus is also known as bus typhus inaction and it is a serious public health problem in the Asia-Pacific area. It threatens one billion peoples are effected worldwide, and causes illness in one...
FORMULATION AND EVALUATION OF ORMELOXIFENE FAST DISSOLVING TABLETS
The objectives of the present work were to enhancedissolution and solubility of slightly water soluble ormeloxifene hydrochloride and formulate fast dissolving tablets. The research work was two-phase process; the first...