Anti-Cancer potentials of the plant Aquilaria malaccensis leaves
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 3
Abstract
In the present study the ethanolic extract of Aquilaria malaccensis Agar wood leaves before inoculation BF and after inoculation AF was evaluated for its anticancer potentials The leaf extracts BF and AF was subjected to invitro cytotoxicity studies on EAC cells normal spleen cells and DLA cells The leaf extracts showed dose dependent cytotoxicity with increase in dose The IC50 value for BF and the AF leaf extract was 7909gml and 7920gml respectively The effect on primary spleen cells was observed to be more than 100gml The study concluded that the extract of the said plant leaves has significant potential anticancer activity All these results clearly indicate that the crude extract has a remarkable capacity to inhibit the growth of Ascites tumor induced by EAC cell line in animals Keywords Anticancer Aquilaria malaccensis EAC cell line
Authors and Affiliations
Karunakar Hegde, Fathima Jazeela M A, Vijetha Poojary K, Satish S
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