Anti-Cancer potentials of the plant Aquilaria malaccensis leaves
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 3
Abstract
In the present study the ethanolic extract of Aquilaria malaccensis Agar wood leaves before inoculation BF and after inoculation AF was evaluated for its anticancer potentials The leaf extracts BF and AF was subjected to invitro cytotoxicity studies on EAC cells normal spleen cells and DLA cells The leaf extracts showed dose dependent cytotoxicity with increase in dose The IC50 value for BF and the AF leaf extract was 7909gml and 7920gml respectively The effect on primary spleen cells was observed to be more than 100gml The study concluded that the extract of the said plant leaves has significant potential anticancer activity All these results clearly indicate that the crude extract has a remarkable capacity to inhibit the growth of Ascites tumor induced by EAC cell line in animals Keywords Anticancer Aquilaria malaccensis EAC cell line
Authors and Affiliations
Karunakar Hegde, Fathima Jazeela M A, Vijetha Poojary K, Satish S
Keywords
Related Articles
- EP ID EP478560
- DOI 10.18231/2393-9087.2018.0029
- Views 83
- Downloads 0
RP-HPLC Method development and validation for the simultaneous estimation of Aceclofenac and Rabeprazole Sodium in the bulk and marketed formulation
A simple, accurate and precise RP-HPLC method was developed for the estimation of Aceclofenac and Rabeprazole Sodium in the bulk and marketed formulation. The method was performed by using the mobile phase containing Met...
Seroprevelance of common transfusion transmitted infection among the blood donors
Blood donation is responsible for saving large number of lives but associated with the risk of transfusion-transmissible infections (TTIs). Screening of TTIs among blood donors can be a cost-effective approach to monitor...
Neuropharmacological effects of Albizzia Chinensis extract
Introduction To know the Neuropharmacological effects of Albizzia chinensis extract in rats and miceMaterials and Methods The test compound was evaluated experimentally for its neuropharmacological activities in rats and...
Evaluation of anxiolytic activity of rousvastatin in male albino mice
Objectives: To assess the anxiolytic activity of ROUSVASTATIN in male albino mice. To compare the anxiolytic activity of ROUSVASTATIN with standard drug as diazepam. Materials and Methods: The study was conducted in Phar...
Impact of mass media on Knowledge attitude and practices (KAP) amongst the ANC mothers attending the ICTC at DrRPG Medical College, Tanda
Objectives To know the Impact of Mass Media on Knowledge attitude and practices KAP amongst the ANC mothers attending the ICTC at DrRPG Medical College TandaMaterials and MethodsThis was a Hospital based cross sectional...