Anti-Diabetic Activity Of Polyherbal Formulation On Alloxan Induced Diabetes.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1
Abstract
Diabetes is a metabolic disorder with major complication associated with hyperglycemia, inflammation, foot ulcer, Nerve disorders and sexual depression Plant medicines are readily used in combination rather than in a single form to get maximum benefit from their combined potential. . Therefore a polyherbal suspension containing alcoholic extract of rhizomes of Curcuma caesia, Roxb whole plant of Evolvulus alsinoide ,seeds of Citrullus lanatus , leaves of Gymnema sylvestre, stems of Tinospora cordiofolia, fruits of Withania coagulans and seeds of Caesalpenia bonduc was prepared and evaluated for its antidiabetic activity. Antidiabetic activity was studied in Alloxan induced diabetic rats. The standard drug used was Glibenclamide 10mg/kg. polyherbal suspension at both the doses 400mg/kg bw was having significant activity. The weight gain and decrease in blood glucose level was less than that of standard drug. Thus the prepared oral Polyherbal suspensionis safe for use with promising antidiabetic activity.
Authors and Affiliations
Mahajan S. M. , Baviskar D. T, Chaudhari P. M.
Keywords
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