Anti-hyperglycaemic activity of Pergularia daemia (Forssk.) Chiov
Journal Title: The Journal of Phytopharmacology - Year 2014, Vol 3, Issue 1
Abstract
Pergularia daemia (Forssk.) Chiov. is commonly known as ‘Velipparuthi’ and its leaves are traditionally used to treat fevers, rheumatism, liver disorders, emetic and expectorant. The present work is aimed to evaluate the effect of leaves of P. daemia on blood glucose level status in streptozotocin induced diabetic rats. STZ diabetic rats showed decreased levels of blood glucose as compared to normal. Daibetic animals were treated with various extract of P. daemia leaves (100, 200 and 300 mg/kg b.w) for 21 days. Oral administration of P. daemia showed the marked reduction in elevated level of serum glucose as compared with diabetic group at a dose of 100, 200 and 300 mg/kg. The results suggested that oral administration of P. daemia possesses significant antidiabetic potential. It was concluded that antidiabetic effect of P. daemia may due to its bioactive compounds responsible for antidiabetic activity present in the leaves extract.
Authors and Affiliations
P. Vinoth Kumar, N. Ramesh
Keywords
Related Articles
- EP ID EP49542
- DOI -
- Views 211
- Downloads 0
GC-MS analysis and Antioxidant activity of essential oil of Artemisia amygdalina from Kashmir, India
The essential oil composition of the leaves of Artemisia amygdalina, growing in Kashmir, India, along with its antioxidant activity, is reported in the present study. Gas chromatography coupled with mass spectrometry (...
Chlorpyrifos-induced oxidative stress in rat’s brain and protective effect of grape seed extract
Oxidative stress is one of the possible mechanisms resulted from chlorpyrifos toxicity. Therefore, the aim of this study is to evaluate the in vivo effects of chlorpyrifos (7.5 mg/kg, s.c., for 28 days, 1/10 LD50 of CP...
Antiviral activities of Cucumis metuliferus fruits alkaloids on Infectious Bursal Disease Virus (IBDV)
Objective: The toxicity of the alkaloids isolated from the fruit pulp of Cucumis metuliferus was investigated in chicken fibroblast cells. Materials and Methods: The alkaloids from C. metuliferus fruit pulp were isolate...
Comparative effects of aqueuos extract of Phyllanthus amarus and its fractions on urinary excretion in rat
The aim of the present study was to compare the effect of Phyllanthus amarus extracts and its fractions on urinary excretion. Aqueous extract of Phyllanthus amarus was prepared by decoction of the whole plant and lyoph...
Evaluation of antioxidant activity of some wild edible fruits collected from Boda and Kolli hills
Free radicals or highly reactive oxygen species are capable of inducing oxidative damage to human body. Antioxidants are the compounds which terminate the attack of reactive species and reduce the risk of diseases; hen...