Anti-hyperglycaemic activity of Pergularia daemia (Forssk.) Chiov
Journal Title: The Journal of Phytopharmacology - Year 2014, Vol 3, Issue 1
Abstract
Pergularia daemia (Forssk.) Chiov. is commonly known as ‘Velipparuthi’ and its leaves are traditionally used to treat fevers, rheumatism, liver disorders, emetic and expectorant. The present work is aimed to evaluate the effect of leaves of P. daemia on blood glucose level status in streptozotocin induced diabetic rats. STZ diabetic rats showed decreased levels of blood glucose as compared to normal. Daibetic animals were treated with various extract of P. daemia leaves (100, 200 and 300 mg/kg b.w) for 21 days. Oral administration of P. daemia showed the marked reduction in elevated level of serum glucose as compared with diabetic group at a dose of 100, 200 and 300 mg/kg. The results suggested that oral administration of P. daemia possesses significant antidiabetic potential. It was concluded that antidiabetic effect of P. daemia may due to its bioactive compounds responsible for antidiabetic activity present in the leaves extract.
Authors and Affiliations
P. Vinoth Kumar, N. Ramesh
Keywords
Related Articles
- EP ID EP49542
- DOI -
- Views 217
- Downloads 0
Antimicrobial activity of some plant species used for the medical purpose in Turkey
İn this study, the antimicrobial activities of eight species plants, used for treatment of various diseases, were investigated. The extracts of Rhus coriaria L., Pistacia terebinthus L. subsp. palestina, Centaurea virga...
Antimicrobial effects of a crude plant lectin isolated from the stem of Tinospora tomentosa
Crude plant lectins were isolated from the stem of Tinospora tomentosa and found its antibacterial and antifungal effects. Lectins were isolated by ammonium sulphate precipitation method. Presence of carbohydrate and p...
Standardization of Haridradi churna- physicochemical assay and HPTLC profile
Haridradi churna, a polyherbal preparation containing Haridra (Curcuma longa Linn.), Devadaru (Cedrus deodar Roxb), Lodhra (Symplocos racemosa Roxb), Priyangu (Callicarpa macrophylla Vahl) and Yastimadhu (Glycyrrhiza g...
Withania somnifera attenuates nicotine induced locomotor sensitization and withdrawal symptoms in mice
Objective: To investigate the effect of withania somnifera extract (WSE) on nicotine mediated reinforcement effect and withdrawal symptoms which attributed for the addiction liabilities of nicotine. Methods: In Swiss a...
GC–MS study on ethanolic extract of Vetiveria lawsonii root
The present study was focused to scrutinize the presence of phytoconstituents in the ethanolic extract of Vetiveria lawsonii root using GC-MS. The GC-MS analysis of Vetiveria lawsonii root was performed using Agilent 6...