Anti-inflammatory studies on a saponin albichinoside
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2019, Vol 5, Issue 4
Abstract
Introduction Pain and inflammation are a day to day affliction for all living beings Mankind has for years been trying to relieve the agony of pain inflammation through various means with a large amount of success Still we have not been able to produce the ideal analgesic or the ideal antiinflammatory drug The objective of this study was to evaluate a saponin albichinoside with respect to its ability to relieve pain and or show antiinflammatory activityMaterials and Methods The study was conducted on rats The saponin was evaluated for its effects on acute subacute chronic and immunological inflammation by using standard antiinflammatory study protocolsResults The test substance showed significant inhibition of acute subacute and chronic inflammation produced by immunological and nonimmunological methods in rats These activities were qualitatively less as compared to indomethacin This activity was like that of nonsteroidal antiinflammatory agentsConclusion The test substance has moderate antiinflammatory activity which could be by means of inhibition of prostaglandin synthesis and the complementKeywords Saponin Antiinflammatory Animals
Authors and Affiliations
Dinesh Kansal, Naresh Naresh, Anjna Sharma
Keywords
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- EP ID EP478571
- DOI 10.18231/2393-9087.2018.0039
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