ANTI OXIDANT ACTIVITY OF SYZYGIUM CUMINI L. LEAVES: EFFECT OF EXTRACTION SOLVENTS
Journal Title: Mintage journal of pharmaceutical and medical sciences - Year 2018, Vol 7, Issue 6
Abstract
Aim: Toxicity of synthetic anti-oxidants is a matter of concern. Therefore, search for natural anti-oxidant was continuously going on and even extended to the field of medicinal plants. Syzygium cumini Linn (S. cumini L.) is a medicinal plant. Anti-oxidant activity of S. cumini L. leaves is known in literature. As biological activity of a plant varies with nature of extraction solvents, aim of the present work was to examine effect of extraction solvents on in vitro anti-oxidant activity of S. cumini L. leaves. Material & Methods: Plant leaves were collected and identified by the taxonomist. Solvents like ethanol, methanol, acetone, ethyl acetate, chloroform, petroleum ether were used for extraction of the plant leaves and in vitro antioxidant activity of the extracts was checked by superoxide anion generation with the help of linoleic acid peroxidation assay, xanthine-xanthine oxidase assay and with DPPH photometric assay. Flavonoids, ascorbic acid, total phenol and carotenoids contents of the extracts were also estimated. Results: Results showed that methanolic extract of the leaves had maximum in vitro anti-oxidant activity. Methanolic extract also contained high amounts of flavonoids, ascorbic acid, total phenol and carotenoids Conclusion: Methanolic extract of S. cumini L. leaves may be further investigated for search of natural anti-oxidant compounds.
Authors and Affiliations
Prasenjit Mitra, Prasanta Kumar Mitra, Tanaya Ghosh
Keywords
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