ANTIBACTERIAL ACTIVITY OF DAUCUS CAROTA (CARROT) PEEL EXTRACT ON SOME SELECTED CLINICAL ISOLATES FROM MARYAM ABACHA WOMEN AND CHILDREN HOSPITAL, SOKOTO
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 4
Abstract
The antibacterial activity of Daucus carota (Carrot) peel extract was evaluated using clinical bacterial isolates obtained from Maryam Abacha Women and Children Hospital, Sokoto. Active constituents of Daucus carota peel were extracted using aqueous and methanol as solvents, varying concentrations of the extracts (25-200mg/ml) were assayed against S. aureus, E. coli, and P. aeruginosa; the method used was agar well diffusion method and considerable zones of inhibition were recorded against S. aureus and E. coli while P. aeruginosa showed no zone of inhibition at 200mg/ml concentration, aqueous extract showed maximum zone of inhibition. Ciprofloxacin was used as standard antibiotic to compare zone of inhibition with that of extract. This study showed that S. aureus and E. coli were sensitive to both extracts. Minimum Inhibitory Concentration (MIC) values against all the organisms were also recorded, but no Minimum Bactericidal Concentration (MBC) was recorded. It can be concluded from this study that overall antibacterial activity of Daucus carota peel extracts was quite reasonable against S. aureus and E. coli and provides data that may be supportive point about its medicinal values.
Authors and Affiliations
Dr. Muntari Bello
Keywords
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