Abstract

This study investigated the antibacterial activities of methanolic crude extracts of Vitex parviflora (V. parviflora) leaves and stem and Cyanthillium cinereum (C. cinereum) leaves and roots. Crude methanolic extracts of V. parviflora and C. cinereum were tested for their antibacterial activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis. The leaf and stem extracts of V. parviflora and root extracts of C. cinereum exhibited high antibacterial activity against Staphylococcus aureus. Increasing concentration of the V. parviflora leaves and roots crude extracts resulted in an increasing antistaphylococcal activity as exhibited by increasing diameters of zone of inhibition. Root extracts of C. cinereum exhibited inverse dose-response relationship. The anti-staphylococcal activity was the highest at the lowest concentration (25 mg/mL) and it decreased as the concentration increased. This study established the anti-staphylococcal activity of methanolic crude extracts of V. parviflora leaves and stem and C. cinereum roots. This study also validated the use of these plants in folkloric medicines in the indigenous communities in the Philippines.

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