Antibacterial and Antifungal Activity of Litsea monopetala Leaves on Selected Pathogenic Strains
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 12, Issue 4
Abstract
Aims: To evaluate the antibacterial and antifungal activity of some solvent extracts of Litsea monopetala (LM) leaves. Study Design: Examination of antibacterial and antifungal activity of petroleum ether fraction (PEF), chloroform fraction (CLF), ethyl acetate fraction (EAF) and crude methanol extract (CME) of Litsea monopetala (LM) leaves. Place and Duration of Study: Department of Pharmacy, Southeast University, Dhaka-1213, Bangladesh, from September to November 2014. Methodology: Fresh LM leaves were extracted with methanol followed by fractionation. Antibacterial and antifungal activities of the crude extract were determined by using the Agar disk diffusion method against gram positive, gram negative bacterial and fungal strains. Results: All tested plant extracts, showed varying zones of inhibition against bacteria and fungi tested. The zone of inhibition for bacteria was found to be in the range from 5 to 15 mm and 5 to 13 mm for fungi. The CME and EAF of the methanolic extract of LM has greater antibacterial activity against all tested gram positive and gram negative bacteria compare to other fraction. CME and EAF has also strong antifungal activity against tested fungi except Candida albicans in which CLF showed maximum antifungal activity. Conclusion: The present study shows that LM leaves possess an excellent source of natural antibacterial and antifungal agents which could be developed in the treatment of bacterial and fungal diseases.
Authors and Affiliations
Md. Fakhrul Hasan, Mohammed Ashraful Iqbal, Md. Sahab Uddin
Keywords
Related Articles
- EP ID EP349724
- DOI 10.9734/EJMP/2016/23658
- Views 98
- Downloads 0
Quality Evaluation of Herbal Tea Blends from Ginger and Pavetta crassipes
Tea-like product (green tea) was developed using ginger (Zingiber officinale, Rose) and Pavetta crassipes k. schum blends. Samples were blended in the following ratios (ginger/pavetta): 100/0 (sample A), 80/ 20 (sample B...
Ameliorative Effects of the Methanolic Extract of the Rind of Citrullus lanatus on Lead Acetate Induced Toxicity on Semen Parameters and Reproductive Hormones of Male Albino Wistar Rats
Aims: The present study investigated the effects of the methanolic extract of the rind of Citrullus lanatus on lead acetate induced toxicity on semen parameters, reproductive hormone assay and testicular histology in mal...
Phytochemical and Anti-diarrhoeal Properties of Methanolic Leaf Extract of Maerua crassifolia Forssk
Maerua crassifolia Forssk. Leaf is used in African traditional medicine for management of gastrointestinal disorders. The anti-diarrhoeal activity of the methanol extract of Maerua crassifolia leaf was investigated in ra...
Antioxidant, Anti-proliferation and Cytotoxicity Activities of Gossypium hirsutum toward Standard HepG2, A549, MCF-7 and U87 Cancer Cell Lines Compared to Huvec, 3T3 Normal Cells
Aims: Cancer has become a growingly medical and health care issue with no effective treatment modality. Chemotherapy besides existing drugs is associated with severe adverse side effects. The present study was aimed to e...
Phytochemical Screening, Antifungal and Antibacterial Effect of Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum Used in Traditional Medicine in Yamboro (Central African Republic)
The knowledge of traditional medicine has always guided the search for new cures. Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum, (Rutaceae) are used as medicinal plants in Central African Republic for bacteria a...