Antibacterial and Antifungal Activity of Litsea monopetala Leaves on Selected Pathogenic Strains
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 12, Issue 4
Abstract
Aims: To evaluate the antibacterial and antifungal activity of some solvent extracts of Litsea monopetala (LM) leaves. Study Design: Examination of antibacterial and antifungal activity of petroleum ether fraction (PEF), chloroform fraction (CLF), ethyl acetate fraction (EAF) and crude methanol extract (CME) of Litsea monopetala (LM) leaves. Place and Duration of Study: Department of Pharmacy, Southeast University, Dhaka-1213, Bangladesh, from September to November 2014. Methodology: Fresh LM leaves were extracted with methanol followed by fractionation. Antibacterial and antifungal activities of the crude extract were determined by using the Agar disk diffusion method against gram positive, gram negative bacterial and fungal strains. Results: All tested plant extracts, showed varying zones of inhibition against bacteria and fungi tested. The zone of inhibition for bacteria was found to be in the range from 5 to 15 mm and 5 to 13 mm for fungi. The CME and EAF of the methanolic extract of LM has greater antibacterial activity against all tested gram positive and gram negative bacteria compare to other fraction. CME and EAF has also strong antifungal activity against tested fungi except Candida albicans in which CLF showed maximum antifungal activity. Conclusion: The present study shows that LM leaves possess an excellent source of natural antibacterial and antifungal agents which could be developed in the treatment of bacterial and fungal diseases.
Authors and Affiliations
Md. Fakhrul Hasan, Mohammed Ashraful Iqbal, Md. Sahab Uddin
Keywords
Related Articles
- EP ID EP349724
- DOI 10.9734/EJMP/2016/23658
- Views 118
- Downloads 0
Competitive Biodiversity of Human and Vascular Plant Species: The Implications for Pharmaceutical Industries, Health and World Economy Part- 2
Aims: The world population is increasing at alarming rate vis-à-vis the need for health and many vascular medicinal plants are being destroyed. So we risk upsetting the ecological balance of the earth. Methodology: To a...
Nephroprotective and Curative Assessment of an Aqueous Seed Extract of Parkia clappertoniana Keay in Gentamicin-induced Renal Damage in Sprague-dawley Rats
Aim: To assess the nephroprotective and curative effects of an aqueous seed extract of Parkia clappertoniana on gentamicin-induced renal damage (GIRD) in Sprague-Dawley rats. Study Design: Experimental Place and Duration...
Characterization of Phenolic Compounds of Ulva rigida (Chlorophycae) and Its Antioxidant Activity
Ulva rigida is a worldwide distributed green alga and is commenly used for human nutrition. Extracts of this seaweed were shown anti-hypercholestierinemic, antioxidant and anti-hyperglycemic activities. The antioxidant e...
Ethnomedicinal Survey of Plants Used for the Management of Hypertension Sold in the Makola Market, Accra, Ghana
Hypertension is a highly prevalent public health problem among Africans, including Ghanaians, and it is a major risk factor for cardiovascular diseases such as congestive heart failure, kidney disease, and coronary arter...
Chemical Composition and In vitro Studies of the Essential Oil and Aqueous Extract of Pelargonium graveolens Growing in Jordan for Hypoglycaemic and Hypolipidemic Properties
Aims: This study aimed to analyze the chemical composition of essential oil of Pelargonium graveolens L. Her. ex Ait. growing in Jordan and to test the efficacy of the leaves aqueous extract and essential oil against pan...