Antibacterial and Antioxidant Potential of Ziziphus jujube, Fagonia Arabica, Mallotus phillipensis and Hemidesmus Indicus
Journal Title: Jordan Journal of Pharmaceutical Sciences - Year 2022, Vol 15, Issue 3
Abstract
Phytochemicals present in plants are a major source of imparting different medicinal properties to the plant. Four medicinal plants, i.e., Ziziphus jujube Mill., Fagonia arabica L., Mallotus phillipensis (Lam.) Müll.-Arg. and Hemidesmus indicus (L.) Schult were evaluated for their antibacterial and antioxidant potentials. Chemical analysis of ethanol and ethyl acetate extract of these plants revealed the presence of various phytochemicals in them. Antibacterial activity of extracts was measured against a Bacillus and a Pseudomonas spp. Among all of the extracts, M. phillipensis ethyl acetate extract gave maximum zone of inhibition (14mm) against Bacillus spp. Minimum inhibitory concentration of M. phillipensis ethyl acetate extract was 62.5mg/L. M. phillipensis extract was found to exhibit the maximum bacterial efflux pump inhibition potential (155%). Due to these antibacterial properties, twelve components of M. phillipensis were separated by TLC. Out of these 12, the component showing antibacterial potential was subjected to GCMS analysis which indicated that phthalic acid was the bioactive component responsible for this activity. Antioxidant potential of all extracts was also estimated by various assays where M. phillipensis had maximum potential among all. In conclusion, M. phillipensis extract had maximum antibacterial and antioxidant potential. The bioactive components isolated from this plant can further be used in pharmaceutical industries.
Authors and Affiliations
Rimsha Dilshad, Rida Batool
Keywords
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