Antibacterial Effects of Azadirachta indica Leaf and Bark Extracts in Clinical Isolates of Diabetic Patients
Journal Title: National Journal of Integrated Research in Medicine - Year 2010, Vol 1, Issue 5
Abstract
Background: Antibacterial activities of crude Azadirachta indica (neem) bark and leaf extracts were investigated in bacterial species isolated from clinical samples of diabetic individuals. Methods and Material: Nine different dilutions of methanolic bark and leaf extracts were tested for this purpose in agar well diffusion method. Results: Both the extracts were active against Gram positive as well as Gram negative strains. Zones of inhibition produced by different bacteria for different concentrations were summarized by linear regression. Highest activities were exhibited for coagulase negative Staphylococcus (CONS) by both bark and leaf extracts, Y = 16.95 + 0.19X and Y = 18.90 – 0.70X, respectively. Conclusions: Results indicate that exhaustive studies involving identification of specific compounds in neem extracts and testing their activities in diabetic samples would be worthwhile considering steep emergence of multidrug resistant species in diabetic infections and infections in general.
Authors and Affiliations
Ms. P. Chaturvedi, Dr. A. Bag, Dr. V. Rawat, Dr. N. S. Jyala
Keywords
Related Articles
- EP ID EP40121
- DOI -
- Views 398
- Downloads 0
Effect of Clonidine Addition To Hyperbaric 0.5% Bupivacaine For Spinal Anaesthesia In Lower Limb Surgery [A Comparative Study]
Background: The use of subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgery. Regional anaesthesia is generally well tolerated by all patie...
Antibiotic Resistance Pattern of Urinary Tract Isolates of Escherichia coli from Kumaun Region
Background: Concurrent resistance to antimicrobials of different structural classes has arisen in a multitude of bacterial species and may complicate the therapeutic management of infections, including those of the uri...
The Study of Median and Lateral Articular Facets of Atlas Vertebra For Dens
As atlanto- axial joints are the most complex joints of the axial skeleton, both anatomically and kinematically, comprehensive knowledge of spinal kinematics is of paramount importance for an understanding of all aspec...
Multicentric Morphometric Study of Dry Human Sacrum Of Indian Population In Gujarat Region
Sacrum is a large triangular bone. It is formed by fusion of five sacral vertebrae and forms the caudal region of the vertebral column. It forms posterosuperior wall of the pelvic cavity wedged between the two hip bone...
Practical Aspects of Calculation, Expression and Interpretation Of Urine Albumin Measurement
There is a large variation for estimation of albumin in urine between different laboratories. Clinical practice guidelines for the urine albumin measurements have been issued by professional organizations in several co...