Antibiotic profile of Pseudomonas aeruginosa strains isolated in a teritiary care centre
Journal Title: Indian Journal of Microbiology Research - Year 2018, Vol 5, Issue 1
Abstract
Introduction Multidrug resistance among clinical samples has emerged as a major problem in clinical settings Pseudomonas aeruginosa is an opportunistic nosocomial pathogen inherently resistant to many drugs and is able to acquire resistance to all effective antimicrobial drugs Multidrugresistant MDR P aeruginosa is an emerging cause of mortality and morbidity which causes 460 nosocomial infections worldwideAim The aim of the present study was to determine the antimicrobial susceptibility pattern of P aeruginosa isolates from various clinical samples in a tertiary care centreMaterials and Methods 100 Pseudomonas aeruginosa isolates from various clinical samples collected in a tertiary care hospital over a period of 6 months were included in the study Antimicrobial susceptibility testing was performed using KirbyBauer disc diffusion method Interpretation was done according to the CLSI guidelines Quality control was performed by using a standard strain of Pseudomonas aeruginosa ATCC 27853Result Among the entire gram negative organism isolated from different samples Pseudomonas aeruginosa isolates were around 29 Out of the 100 Pseudomonas aeruginosa isolates studied 87 were sensitive to Imipenem 69 to Amikacin 82 to PiperacillinTazobactum 69 to Aztreonam 31 to third generation cephalosporins 34 to Gentamicin amp 47 to Ciprofloxacin respectivelyConclusion In order to control antimicrobial resistance and to keep it in check it is necessary to practice effective antibiotic policies frequent surveillance programs and adequate infection control measuresKeywords Drug Resistance Disc diffusion method Pseudomonas aeruginosa
Authors and Affiliations
Sindhu Cugati, Sharanya K, Chitralekha Saikumar
Keywords
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- EP ID EP473847
- DOI 10.18231/2394-5478.2018.0024
- Views 61
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