ANTIBIOTIC RESISTANCE DYNAMICS OF ACINETOBACTER SPP. IN ICU
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 2
Abstract
Objective: to analyze the dynamics of antibiotic resistance of Acinetobacter spp. isolated from patients in ICU. To identify effective antibiotics against isolated strains. Material and methods. We analyzed the isolated strains and analyzed the results of determining the sensitivity of Acinetobacter spp. to antibacterial drugs. The pathogens were isolated from ICU patients in 2008-2019. Clinical material for microbiologic examination included wound secretions, bronchoalveolar lavage, abdominal cavity exudate, abscess contents, bile, urine, and blood. Microbiological studies were carried out in the laboratories of microbiological of the State Institution “RSSPMC for surgery named after V.Vakhidov" Results. Due to the introduction of recommended protocols for antibacterial prophylaxis and treatment, methods of monitoring the effectiveness of antimicrobial therapy, the introduction of forecasting methods (identification of risk groups and more targeted antibiotic prophylaxis of nosocomial infections), effective criteria for ventilator modes, approaches to pathogenetic therapy, nutritional support, etc. since 2012, there is a decrease in the frequency of purulent-septic complications, so that in 2012-2019 in the cardiac block, it was from 1.5-1.3 to 0.3-0.1%, in the abdominal block - from 1.0-1.9 to 0.5-0.2%, in the thoracic block - from 0.7-0.5 to 0.03-0.02%. Conclusion. The increasing antibiotic resistance of Acinetobacter spp. causes the necessity to study antibiotic grams of all strains isolated from patients for adequate choice of means of effective antibiotic therapy. The obtained data were used to optimize empirical antibiotic therapy in patients with purulent-septic complications in ICU.
Authors and Affiliations
Ibadov Ravshan Alievich, Shanieva Zulfiya Aymurzaevna, Ibragimov Sardor Khamdamovich
Keywords
Related Articles
- EP ID EP732569
- DOI 10.5281/zenodo.10700638
- Views 62
- Downloads 0
THE STUDY OF THE PROBLEM OF ADOLESCENT MENTAL DEVELOPMENT AND ABILITIES IN MODERN PSYCHOLOGY
The article explores the notions of "adaptation" and "socialization" in adolescents, evaluates the indicators of effective adaptation, and highlights instances of adolescent maladaptation.
INDICATORS OF THE NEUROLOGICAL STATUS OF COGNITIVE IMPAIRMENT IN POSTTRAUMATIC ENCEPHALOPATHY IN CHILDREN
The article presents the results of a survey of 46 children aged 7 to 18 years with a diagnosis of post-traumatic encephalopathy. The examination and assessment of the neurological status were carried out according to a...
THE SIGNIFICANCE OF TEACHING KNOWLEDGE OF HOMOGENEOUS MAGNETIC FIELD THROUGH THE ANDROID PROGRAM IN A SCHOOL PHYSICS COURSE
This article describes the methodology and importance of teaching the "Magnetic field" section of physics for schoolchildren through the Android program, focusing on topics such as magnetic field flow and finding the tor...
ACADEMIC MOBILITY AS A TOOL FOR INTERNATIONAL INTEGRATION
This thesis explores academic mobility as a key tool for fostering international integration in education. Academic mobility encompasses the movement of students, faculty, and researchers across borders to engage in educ...
CHANGES IN THE ORAL MUCOSA DUE TO GASTROINTESTINAL TRACT DISEASE
The article provides an overview of the interconnections between the gastrointestinal tract (GIT) and the oral cavity, emphasizing the priority of the GIT. Special attention is given to the complex pathophysiological rel...