Antibiotic Susceptibility Pattern of Acinetobacter Spp Isolated From ICU at Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Acinetobacter is a gram negative coccobacillus that can cause infections in the respiratory tract, blood, soft tissue, urinary tract and CNS. Their ubiquitous nature in the ICU environment coupled with inadequate infection control practices have continuously raised the incidence of Acinetobacter infection over the past two decades. Aims and Objectives: To determine the antibiotic susceptibility pattern of Acinetobacter spp. isolated from ICU patients at RIMS, Ranchi. Material and Methods: The study was done in the Department of Microbiology RIMS, Ranchi from Nov 2016 to April 2017. Specimens were obtained from ICU wards. Total 152 samples were collected, processed and AST was done by using Kirby Bauer method as per the CLSI guidelines. Results: Among 152 samples, 51 (33.55%) were culture positive. From 51 culture positive samples, Acinetobacter spp .were isolated in 8 (15.68%) samples. The number and percentage of Acinetobacter in various clinical sample were sputum 5 (62.5%), blood 2 (25%) and urine 1 (12.5%). The strains showed maximum resistance to cefotaxime (100%) and ceftazidime (100%) followed by ciprofloxacin (87.5%), ampicillin (87.5%), gentamicin (75%) and amikacin (62.5%). All the strains were sensitive to colistin (100%), imipenem (75%), cefoperazone-sulbactum (62.5%) and piperacillin-tazobactum (50%). Conclusion: The emerging resistant strains of Acinetobacter infections have led to fewer treatment options. Due to these limited therapeutic options, prevention and infection control measures are essential, including not only traditional measures but also antibiotic control strategies in the ICU.
Authors and Affiliations
Amber Prasad, Versha Priyadarshini, Ashok Kumar Sharma, Manoj Kumar, Megha Priyadarshini, Kumari Seema
Keywords
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- EP ID EP540044
- DOI 10.21276/ijmrp.2018.4.2.063
- Views 62
- Downloads 0
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