ANTIBIOTIC SUSCEPTIBILITY PATTERNS OF AEROBIC BACTERIAL ISOLATES CAUSING WOUND INFECTIONS AMONG THE PATIENTS ATTENDING TO SANTHIRAM GENERAL HOSPITAL, NANDYAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 30
Abstract
BACKGROUND The increasing trends in the rate of the antibiotic resistance have now become a serious and an increasingly common concern with severe implications, especially in the surgical departments. These multidrug resistance patterns which include ESBLs, AmpC ßlactamases and metallo-ß-lactamases have emerged as the most worrisome mechanisms of resistance among the gram-negative bacteria, which pose a therapeutic challenge to the healthcare settings. MATERIALS AND METHODS This descriptive study was undertaken to evaluate the profile of aerobic pyogenic bacteria in various pus isolates along with the changing trends in antimicrobial resistance in a tertiary hospital in Nandyal from January 2017 to December 2017. A total of 283 bacterial isolates from 577 clinical samples, which were received over a period of one year were processed. After their identification and their antimicrobial susceptibility testing, they were then screened for the multidrug resistance. RESULTS Among the 283 isolates, most predominant organism was Escherichia coli 63 (22.18%) followed by Pseudomonas aeruginosa 60 (21.13%) and Staphylococcus aureus 58 (20.42%). The antibiogram of gram-positive cocci revealed that they were most susceptible to Vancomycin (100%) and Linezolid (100%). Gram-negative Bacilli are susceptible to Imipenem (96.23%), Cefoperazone + Sulbactam (77.22%) and Netilmicin (75.47%). Of the 212 gram-negative isolates, 143 (67.45%) were ESBL producers followed by 36 (16.98%) AmpC producers and 7 (3.30%) metallo-β-lactamase (MBL) producers. The major ESBL and AmpC producer was Klebsiella pneumoniae, while the MBL production was mainly observed in Pseudomonas aeruginosa. CONCLUSION The high prevalence of the multidrug resistant isolates emphasises the need for a continuous surveillance in the healthcare settings to detect the resistant strains, strict guidelines for the antibiotic therapy and the implementation of infection control measures to reduce the increasing burden of antibiotic resistance.
Authors and Affiliations
Mogalapu Ananda Satya Tej, Sanikommu Sreedevi, Sumanth Kumar G. L. S. , Jinka Balakrishna, Satta Naga Sireesha, Syeda Mariam Seher
Keywords
Related Articles
- EP ID EP538637
- DOI 10.14260/jemds/2018/758
- Views 72
- Downloads 0
ATTITUDES TOWARD BIOSTATISTICS AMONG POST-GRADUATE MEDICAL STUDENTS IN KISHANGANJ, BIHAR
[b]BACKGROUND: [/b]Biostatistics is a basic and vital tool for medical as well as allied science research. In medical education, biostatistics is taught at undergraduate level without emphasis on its practical aspect...
COMPUTED TOMOGRAPHIC EVALUATION OF PULMONARY TUBERCULOSIS AND ITS SEQUELAE
[b] INTRODUCTION[/b]: Tuberculosis is a specific granulomatous disease, caused by mycobacterium tuberculosis. CT scan, particularly HRCT seems to be most useful imaging modality for tuberculous infection and its se...
CYSTICERCOSIS IN THE ORAL CAVITY: A CASE REPORT WITH REVIEW OF LITERATURE
Cysticercosis is caused by the larval stage of Taenia Solium. A middle aged woman presented with a painless solitary nodular swelling on left lateral border of the tongue. Fine needle aspiration cytology revea...
EFFECT OF PROPOLIS ON BONE LOSS PREVENTION- A REVIEW
BACKGROUND Statement of problem- Bone loss caused by excessive osteoclast formation is the major mechanism underlying many bone diseases leading to problems in dentistry, affecting the treatment plan and patient’s qualit...
PSEUDOMONAS- AN EMERGING NOSOCOMIAL PATHOGEN
BACKGROUND Pseudomonas aeruginosa is one of the most common pathogens causing nosocomial infections, which is a major threat to patients’ safety. It is an opportunistic pathogen with innate resistance to many antibiotic...