ANTIBIOTICS USED AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS IN DERMATOLOGICAL DISORDERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 34
Abstract
BACKGROUND Antibiotics are the drugs used for killing or inhibiting growth and multiplication of infectious organisms. Antibiotics are commonly prescribed for treatment of infections. However, antibiotics have immunomodulatory and anti-inflammatory properties and can be used for various non-infectious dermatoses. Dermatologists routinely prescribe antibiotics in treatment of various non-infectious disorders. Tetracyclines can be used in Bullous pemphigoid, Acne vulgaris, Rosacea, Hidradenitis suppurativa, Pyoderma gangrenosum, Linear IgA disease and Dermatitis herpetiformis.1 This clinical study will review anti-inflammatory and immunomodulatory effects of Tetracyclines used in 15 patients of bullous pemphigoid (04), acne vulgaris (06), pyoderma gangrenosum (03) and rosacea (02) along with vitamin B3 (niacinamide). These drugs can be used as steroid sparing agents when other comorbidities are present in elderly patients.
Authors and Affiliations
S. Showkath Ali, T. Praveena, M. Madhavi Lata, Mastan Saheb
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