Anticoccidian Activity of Ethanol Roots Extract of Cassia sieberiana DC in Chickens
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 11, Issue 1
Abstract
Objectives: The aim of this study was to investigate the anticoccidian activity of ethanol roots extract and fractions in chicken experimentally infested by oral administration of coccidia’s oocysts solution. Methods: Ethanol roots extract was fractionated by column chromatography using a gradient polarity of solvents (dichloromethane, ethyl acetate and methanol) and lead to these said fractions. For anticoccidian activity, « Leghorn » chicks were experimentally parasitized by oral administration of Coccidia oocysts solution (Eimeria sp). After detection of oocyts in the chicks droppings and treatments with the extract and fractions, the parasitological examination was carried out in order to determine the number of oocysts in 1 g of faeces. Results: The study had shown that the ethanol extract was more active than the 3 fractions and the reference product (amprolium). The percentages of reduction of the OPG at the end of treatment in groups treated by the ethanol extract (10 and 5 mg/day) were respectively 88.63±7.89% and 74.39±6.81% while that of amprolium was only 58.42±5.78%. The dichloromethane fraction (0.131 mg/day) and the methanol fraction (7.225 mg/day) had similar reduction effect on coccidian (80±7.25 and 81.01±7.03% respectively. Conclusion: The ethanol extract from the roots of Cassia sieberiana and its various fractions had shown an anticoccidian activity.
Authors and Affiliations
Alioune Dior Fall, Oubri Bassa Gbati, William Diatta, Rock Allister Lapo, Kady Diatta-Badji, Mbaye Dieng, Serigne Ibra Mbacke Dieng, Emmanuel Bassene, Louis Joseph Pangui
Keywords
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- EP ID EP349587
- DOI 10.9734/EJMP/2016/21343
- Views 107
- Downloads 0
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