Antidiabetic potential of Musa paradisiaca in Streptozotocin- induced diabetic rats
Journal Title: The Journal of Phytopharmacology - Year 2014, Vol 3, Issue 2
Abstract
Aim: Over the last few decades the role of medicinal plants as a primary tool in the preservation of health and management of diseases is realized with great concern. This is mainly due to the use of synthetic drug molecules that produce harmful side effects, which are comparatively minimal in drugs of plant origin. The Antidiabetic activity of the flowers has been reported in the literature, but not studied systematically all parts of the M. paradisiacal (Linn.). Therefore, we have selected this plant to study all other parts of this in detail for its antidiabetic potential. Methods: The ethanolic extracts of leaves, fruit peels, stems and roots were prepared at room temperature and the extracts showing antidiabetic activity were fractionated into 4 fractions by maceration method (hexane, chloroform, n-butanol solubles an n-butanol insoluble fractions). Results: The ethanolic extracts and the hexane and chloroform fractions of leaves and fruit peels showed promising antidiabetic activity in STZ-s model. Further the isolated compounds from the active fractions did not show the antidiabetic activity. Conclusion: Further work on active molecules from this plant is required to get a lead molecule for the development of a new and potent antidiabetic drug.
Authors and Affiliations
Vijai Lakshmi, S. K. Agarwal, Jamal Akhtar Ansari, Abbas Ali Mahdi, Arvind Kumar Srivastava
Keywords
Related Articles
- EP ID EP49547
- DOI -
- Views 181
- Downloads 0
Wound repair and regeneration potential of the fruits of Terminalia bellarica
The infection at the wound site is a severe kind of problem and it delays regeneration of epidermis and dermis in the wound and slows wound closure. Due to the secretion of microbial enzymes by wound pathogens, a varie...
Study of Diet and Regimen in the Pathogenesis of Hridroga (Heart Diseases) in Ayurveda
Purpose: Hridroga is the disease of marma (vital organ), which is the seat of many vital activities. Hridroga is among those diseases mentioned in ayurveda where in the descriptions is quite brief and ayurvedic viewpoin...
Screening of prescriptions in geriatric population in a tertiary care teaching hospital in north India
The objective of our study was to assess the pattern of prescribing prescriptions and cost analysis among the geriatric patients attending the Medicine Outpatient Department of NIMS Medical College and Hospital, Jaipur...
Standardization of Vyoshadi Saktu a Pathykalpana (Nutritional supplement) in Diabetes
Neuropathy and Cardiac complications are the most common trouble in diabetes mellitus with progressive damage due to complex pathogenesis. Many conventional pharmacological agents were withdrawn from clinical studies e...
A prospective study of prathisaraneeya apamarga kshara in comparison with prathisaraneeya palasha kshara in patients with charmakeela (warts) and kadara (corns)
Background: Charmakeela and Kadara are the diseases which have signs and symptoms similar to Warts and Corns respectively. Objectives: Kshara karma is mentioned under kshudra roga adhikaras by Acharya Sushruta under th...