Antifungal Activity Of Coccinia Indica Extracts Against Fungal Pathogens
Journal Title: International Journal of Pharmaceutical Science Invention - Year 2018, Vol 7, Issue 4
Abstract
In recent years there has been renewed interest in screening plants for novel biologically active products particularly to combat ailments, which have defied synthetics and antibiotics. Medicinal plants offer a vast source of novel natural compounds, often with exciting biological properties. Therefore, the systematic screening of plant extracts or plant derived substances remains an interesting strategy to find new lead compounds. The present study is about the evaluation of antifungal activity. The antifungal activity was tested using dermatophytes like Candida albicans, Microsporum gypsum and Microsporum canis and other fungi on Asthana and Hawker’s and Sabourad’s dextrose agar media. The organic extracts exhibited stronger antifungal activity than the corresponding aqueous extracts. Among all the extracts tested, petroleum ether and methanol extracts showed maximum activity. The gram positive bacteria were more susceptible compared to gram negative bacteria. The cultivated fruit extracts were most significant with larger zones of inhibition (antifungal: 3-8 mm) followed by leaf, root and stem extracts.
Authors and Affiliations
Syed Zeenat Shaheen, Gudikandula Krishna, M. A. Singara Charya
Keywords
Related Articles
- EP ID EP401404
- DOI -
- Views 121
- Downloads 0
Synthetic Utility of Aza Heterocyclics: A Short Review
Azaheterocyclic compounds contain nitrogen atom in the ring. They are of vital importance in the race to improve our understanding of basic chemistry which underlies nearly all of the important life-processes and a large...
QSAR Studies of the Inhibitory Activity of a Series of Substituted Indole and Derivatives Againt Isoprenylcysteine Carboxyl Methyltransferase (Icmt)
HF method, with the basis set 6-31G (d) was employed to calculate quantum some chemical descriptors of 37 substituted Indole. The best descriptors were selected to establish the quantitative structure activity relationsh...
Therapeutic Consequence of Allogeneic Mesenchymal Stem Cell for Duchenne Muscular Dystrophy- Case Study
Duchenne muscular dystrophy (DMD) is an inherited disorder caused by mutation in gene that prevents the translation of dystrophin protein, which leads to massive skeletal muscle wasting. Any form of muscular dystrophy is...
Antibacterial Activity of Some Medicinal Plants Oil Used Against Uti Causing Pathogens
Infections of the urinary tract due to microorganisms affect patients of all age groups and both sexes, and they vary in severity from an unsuspected infection to a condition of severe systemic disease. UTI are generally...
A case of a boy with SOD and 7q11.23 microduplication syndrome
Тheseptooptic dysplasia (SOD) is an extremely heterogeneous condition. The classical triad includes optic nervehypoplasia/aplasia, midline defects, and hypopituitarism. Anomalies of the visual system, CNS, and various sy...