Antifungal Activity Of Coccinia Indica Extracts Against Fungal Pathogens
Journal Title: International Journal of Pharmaceutical Science Invention - Year 2018, Vol 7, Issue 4
Abstract
In recent years there has been renewed interest in screening plants for novel biologically active products particularly to combat ailments, which have defied synthetics and antibiotics. Medicinal plants offer a vast source of novel natural compounds, often with exciting biological properties. Therefore, the systematic screening of plant extracts or plant derived substances remains an interesting strategy to find new lead compounds. The present study is about the evaluation of antifungal activity. The antifungal activity was tested using dermatophytes like Candida albicans, Microsporum gypsum and Microsporum canis and other fungi on Asthana and Hawker’s and Sabourad’s dextrose agar media. The organic extracts exhibited stronger antifungal activity than the corresponding aqueous extracts. Among all the extracts tested, petroleum ether and methanol extracts showed maximum activity. The gram positive bacteria were more susceptible compared to gram negative bacteria. The cultivated fruit extracts were most significant with larger zones of inhibition (antifungal: 3-8 mm) followed by leaf, root and stem extracts.
Authors and Affiliations
Syed Zeenat Shaheen, Gudikandula Krishna, M. A. Singara Charya
Keywords
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